Heart

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by Sandeep Jauhar


  Roberts, John Bingham, 63

  Rohman, Michael, 97

  Roman Catholic Church, 22

  Roman Empire, 40

  romantic love, heart as locus of, 21

  Rome, 42

  Romeis, Peter, 105, 107

  Roosevelt, Franklin Delano, 114–15, 117, 120

  Rosenman, Ray, 126–27

  Ross, Donald, 85

  Royal Infirmary (Edinburgh), 137

  Ruelle, David, 160n

  Russia, 118

  Sacred Heart of Jesus, 22

  St. Louis, 33, 62n, 72; Washington University School of Medicine in St. Louis, 33–38, 42, 47–48, 54, 72

  St. Luke’s Episcopal Hospital (Houston), 190

  St. Petersburg (Russia), 118

  Salem (Massachusetts), 117

  Salt Lake City, 22, 192

  San Francisco Bay Area, 123

  Sauerbruch, Ferdinand, 108

  schizophrenia, 77n

  Schmidt, Pamela, 84–85

  Schneider, Richard, 104, 107, 108

  Scientific American, 127

  Scotland, 137, 157, 160, 220

  Sears, Roebuck, 78

  sedatives, 219

  sedentary lifestyle, 123, 241

  selection bias, 232

  self-experimentation, 102–11, 161

  Separation (Munch), 16

  septal defects: atrial (ASDs), 77, 78, 94; ventricular (VSDs), 78–80, 83–84, 168

  September 11, 2001, terrorist attack, see 9/11

  Seroquel, 223

  Servetus, Michael, 43

  Seuse, Heinrich, 22

  Shakespeare, William, 21

  Shaw, Laura, 139

  shock, 56, 59, 60, 62, 109, 129

  shocks, electrical, see defibrillation

  shortness of breath, 24, 25, 115, 145, 150, 184, 192

  Shumway, Norman, 186–88

  Siddiqui, Mohammed, 209–10

  Siemens echocardiogram machine, 58

  Sigmamotor milk pump, 82

  Sikhs, 29

  Sinai Hospital (Baltimore), 173, 174

  Sinemet, 221, 223

  sinoatrial node, 151–52, 152, 154

  sleep disorders, 210, 219–21, 223–24

  smoking, 13, 70, 126, 134, 144, 233, 242; as cardiovascular risk factor, 54, 120–22, 128, 132, 237; rates of, 13, 118, 238

  snakes, 7–9, 28

  Snow, John,115–17

  Snow White (fairy tale), 12

  sonar, see ultrasound

  Sones, Mason, 134–37, 142, 144, 239

  Sontag, Susan, 7, 12

  South Africa, 183, 186–88

  South Asians, prevalence of heart disease among, 122–23, 234

  spiral waves, 155, 155–57, 156, 159–60, 217, 242

  Stanford University, 187

  startle response, 122, 132, 214, 237, 240

  statins, 110, 232, 234

  stents, 53, 110, 130, 143–44, 220–21, 237

  Sterling, Peter, 124–25, 231, 240

  Stevenson, Lynne Warner, 189

  stimulant drugs, 118

  stomach ulcers, 214

  strokes, 65, 96, 157, 189, 195, 223; risk factors for, 4, 115, 120, 133, 233

  sudden cardiac death, 28, 75, 120–21, 166–67, 176, 226; emotional stress causing, 8–9, 26–28, 31, 129–30, 160, 206–207; prevention of, see defibrillators; ventricular fibrillation as major cause of, 157–58, 171, 192, 211, 220–21, 223–25

  superior vena cava, 104, 175, 176

  supplements, dietary, 147–48, 165, 181

  surgical hypothermia, 77–79, 82

  Sweden, 61, 90–91

  Switzerland, 11n, 140, 171

  sympathetic nervous system, 207, 217, 220–21, 238

  syphilis, 105

  Syracuse University, 159

  Syria, 41

  tachycardia, 174

  Takens, Floris, 160n

  takotsubo cardiomyopathy, 24, 24–26, 31, 124

  tamponade, 56–57, 61–63, 141

  “Termination of Malignant Ventricular Arrhythmias with an Implanted Automatic Defibrillator in Human Beings” (Mirowski), 177

  Texas Instruments, 170

  Thailand, 220

  Threefold Life of Man, The (Böhme), 33

  thrifty genes, 234

  thrombosis, 37, 97, 114, 129, 232, 239

  Time magazine, 84, 95

  tissue death, 37–38, 40

  Tobacco Institute, 121

  Toronto, University of, 93

  transposition of the great arteries, 81

  treadmill stress test, 4

  Trendelenburg, Friedrich, 90

  Trost, Dr., 4–5, 233–34

  Truman, Harry, 115

  tuberculosis, 37, 62, 117

  Tufts University, 117

  Tulane University, 118

  turbulence, 42n, 159–60, 234

  type A personality, 126–27

  ulcers, 214

  ultrasound, 25, 51, 55–56, 58, 60–61, 141, 233; see also echocardiograms

  Ulysses (Joyce), 140

  Unger, Ernst, 107–108

  United Kingdom, incidence of heart disease in, 12–13

  United States: age at first heart attack in, 122; artificial heart programs in, 189–97; cardiac research in, 87–96, 166–70, 172–77; catheters manufactured in, 141; congenital heart defects in, 75; cost of medical devices in, 149; defibrillators implanted in, 207–16; epidemiological studies in, 113, 116–29; first residency program in, 70; heart transplants in, 187–89; incidence of heart disease in, 12, 123; mortality from heart disease in, 87, 113–15, 157–58, 238; stent use in, 144; see also specific states and municipalities

  University Hospital (Zurich), 142

  “Use of Ultrasonic Reflectoscope for the Continuous Recording of the Movements of Heart Walls” (Edler and Hertz), 61

  Utah, University of, Medical Center, 191–92

  vaccinations, opposition to, 165

  Valium, 219

  Vanderbilt University, 189

  Variety Club Heart Hospital (Minneapolis), 80

  vascular inflammation, 128

  vasopressin antagonists, 239

  vegetarian diet, 122, 231, 236

  vena cava, 63, 104, 175, 176

  ventilators, 54, 97, 196

  ventricles, 18, 37–38, 40–47, 59–61, 69, 133, 145; of artificial heart, 190, 192–93; congenital defects of, 75, 78–84, 168; electrophysiology of, 151, 152, 166–67; implantable devices attached to, 170–71, 176, 196, 211; premature contractions of, 206, 233, 241; survival of injuries to, 63–65, 68; see also ventricular fibrillation

  ventricular assist devices (LVADs), 196

  ventricular fibrillation, 9, 137, 146, 157–60, 171–75, 175, 179; animal studies of, 175, 175–76, 205–206; as major cause of sudden cardiac death, 157–58, 171, 192, 211, 220–21, 225; see also defibrillators

  ventricular septal defects (VSDs), 78–80, 83–84, 168

  verruga peruana, 105

  Vesalius, Andreas, 42, 157n

  Veterans Affairs Hospital (Buffalo, New York), 169–70

  Vibrio cholerae, 116n

  Victoria, Queen of England, 115

  Vietnam War, 121

  vigilance, 124, 125n, 137, 240

  voltage, 17, 19, 151, 168

  voodoo death, 27–28, 31, 160

  “‘Voodoo’ Death” (Cannon), 27

  “vulnerable period,” 158–59, 161, 167, 173, 175, 179, 206

  Wake Forest University, 214

  Wang, Thomas, 114

  Wangensteen, Owen, 74, 76, 78, 187

  Warm Springs (Georgia), 115

  Washington, D.C., 65

  Washington University School of Medicine in St. Louis, 33–38, 42, 47–48, 54, 71, 72, 202

  Washkansky, Louis, 188

  Watson, Cecil, 81–82

  Watson, Thomas, 93

  Wayne State University, 94

  White, Paul Dudley, 121

  Whitehall study, 125

  Wilkes College, 94

  Williams, D
aniel Hale, 61–62, 64–67

  World Trade Center, 9/11 terrorist attack on, 3, 201–205

  World War I, 103

  World War II, 73, 99, 111, 113, 114, 117, 118, 166, 173–74

  X-rays, 4–5, 59, 61, 100, 105, 106, 119, 133, 136–37

  Yalta Conference, 114

  yoga, 216, 232, 235, 241

  York (England), 115

  Zionism, 174

  Zoll, Paul, 166–67, 172

  Zurich (Switzerland), 140

  A NOTE ABOUT THE AUTHOR

  Sandeep Jauhar, MD, PhD, is the director of the Heart Failure Program at Long Island Jewish Medical Center. He is the bestselling author of Doctored and Intern and a New York Times contributing op-ed writer. He lives with his wife and their son and daughter on Long Island.

  A Oneworld Book

  First published in Great Britain and Australia by Oneworld Publications, 2018

  This ebook published 2018

  Copyright © Sandeep Jauhar 2018

  The moral right of Sandeep Jauhar to be identified as the Author of this work has been asserted by him in accordance with the Copyright, Designs, and Patents Act 1988

  All rights reserved

  Copyright under Berne Convention

  A CIP record for this title is available from the British Library

  Portions of this book originally appeared in different form in The New York Times and The New England Journal of Medicine

  Hardback ISBN 978-1-78607-295-5

  Trade Paperback ISBN 978-1-78607-472-0

  eISBN 978-1-78607-296-2

  The names and identifying characteristics of some persons described in this book have been changed

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