In Pursuit of Memory
Page 26
2. Singh, Parsaik, et al., ‘Association of Mediterranean diet with mild cognitive impairment and Alzheimer’s disease’.
3. Braniste, Al-Asmakh, et al., ‘The gut microbiota influences blood–brain barrier permeability in mice’.
4. Miklossy, ‘Alzheimer’s disease–a neurospirochetosis’.
5. Frydman-Marom, Levin, et al., ‘Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer’s disease animal models’.
6. Ngandu, Lehtisalo, et al., ‘A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER)’.
Chapter 11: Exercise
1. Nelson, Gard, Tabet, ‘Hypertension and inflammation in Alzheimer’s disease’.
2. Rockwood, Lindsay, McDowell, ‘High blood pressure and dementia’.
3. Nelson and Tabet, ‘Slowing the progression of Alzheimer’s disease’.
4. Erikson, Voss, et al., ‘Exercise training increases size of hippocampus and improves memory’.
5. Farina, Rusted, Tabet, ‘The effect of exercise interventions on cognitive outcome in Alzheimer’s disease’.
Chapter 12: Brain Training
1. L. Sieg, Special Report–Can Japan’s youth save their ageing nation, 2001, http://uk.reuters.com/article/uk-japan-youth-idUKTRE71E1OY20110215
2. Alzheimer’s Society, Brain Training Trial, 2015, https://www.alzheimers.org.uk/site/scripts/documents_info.php?documentID=3119
3. Mozolic, Hayasaka, Laurienti, ‘A cognitive training intervention increases resting cerebral blood flow in healthy older adults’.
4. Wilson, Mendes de Leon, et al., ‘Participation in cognitively stimulating activities and risk of incident Alzheimer disease’.
5. Aleman, Our Ageing Brain, p.125.
6. Snowdon, Aging with Grace, p.118.
Chapter 13: Sleep
1. Moran, Lynch, et al., ‘Sleep disturbance in mild to moderate Alzheimer’s disease’.
2. J. E. Kang, Lim, et al., ‘Amyloid-β dynamics are regulated by orexin and the sleep–wake cycle’.
3. Roh, Huang, et al., ‘Disruption of the sleep–wake cycle and diurnal fluctuation of β-amyloid in mice with Alzheimer’s disease pathology’.
4. Nedergaard, ‘Garbage truck of the brain’.
5. M. P. Walker, ‘The Mysteries of Sleep’, https://www.youtube.com/watch?v=rOI45ntO0iA
6. Mander, Marks, et al., ‘β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation’.
7. Lucey and Holtzman, ‘How amyloid, sleep and memory connect’.
Chapter 14: Regeneration
1. Yamanaka, Lasker Lecture at Albert Einstein College of Medicine, https://www.youtube.com/watch?v=DQNoyDwCPzM
2. Thomson, Itskovitz-Eldor, et al., ‘Embryonic stem cell lines derived from human blastocysts’.
3. Takahashi and Yamanaka, ‘Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors’.
4. Takahashi, Tanabe, et al., ‘Induction of pluripotent stem cells from adult human fibroblasts by defined factors’.
5. Van der Worp, Howells, et al., ‘Can animal models of disease reliably inform human studies?’.
6. Warren, Tompkins, et al., ‘Mice are not men’.
7. Seok, Warren, et al., ‘Genomic responses in mouse models poorly mimic human inflammatory diseases’.
8. De Souza, ‘Mouse model challenged’.
9. Choi, Kim, et al., ‘A three-dimensional human neural cell culture model of Alzheimer’s disease’.
10. Hallett, Cooper, et al., ‘Long-term health of dopaminergic neuron transplants in Parkinson’s disease patients’.
11. Blurton-Jones, Kitazawa, et al., ‘Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease’.
12. Mukherjee, Laws of Medicine (TED), p.18.
13. Lapillonne, Kobari, et al., ‘Red blood cell generation from human induced pluripotent stem cells’.
14. Tang, Hammack, et al., ‘Zika virus infects human cortical neural progenitors and attenuates their growth’.
15. Paul Knoepfler in M. Scudellari, ‘How iPS cells changed the world’.
Chapter 15: Young Blood
1. McCay, Pope, et al., ‘Parabiosis between old and young rats’.
2. Learoyd, ‘The history of blood transfusion prior to the 20th century’.
3. Bert, ‘Expériences et considérations sur la greffe animale’.
4. I. M. Conboy, M. J. Conboy, et al., ‘Rejuvenation of aged progenitor cells by exposure to a young systemic environment’.
5. Von Radowitz, ‘Vampire therapy’.
6. Villeda, Plambeck, et al., ‘Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice’.
7. Villeda, Luo, et al., ‘The ageing systemic milieu negatively regulates neurogenesis and cognitive function’.
8. Harrison, Strong, et al., ‘Rapamycin fed late in life extends lifespan in genetically heterogeneous mice’.
9. De Grey, Ending Aging, p.163.
Chapter 16: Seeds of Dementia
1. Braak and Del Tredici, ‘Alzheimer’s pathogenesis’.
2. Meyer-Luehmann, Coomaraswamy, et al., ‘Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host’.
3. Lipinski and Hopkins, ‘Navigating chemical space for biology and medicine’.
4. Eisele, Obermüller, et al., ‘Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis’.
5. R. M. Ridley, Baker, et al., ‘Very long term studies of the seeding of beta-amyloidosis in primates’.
6. Jaunmuktane, Mead, et al., ‘Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy’.
7. Prusiner, Madness and Memory, p.202.
8. To allay fears, the UK’s Department of Health created a helpline for anyone who received cadaveric growth hormone and is concerned about their risk of CJD or Alzheimer’s.
9. A. Miller, J. Dowd, M. D. Heath, S. M. D. Morris, S. Mosley, P. Nash,… R. Williams, After the storm? UK blood safety and the risk of variant Creutzfeldt-Jakob Disease, House of Commons Science and Technology Committee, www.publications.parliament.uk/pa/cm201415/cmselect/cmsctech/327/327.pdf
10. Anon., ‘Alzheimergate? When miscommunication met sensationalism’.
11. Gye, ‘Chief medical officer is accused of trying to discredit impact of controversial study on Alzheimer’s before findings were published’.
12. A. Abbott, ‘The red-hot debate about transmissible Alzheimer’s’.
Chapter 17: Looking but Not Seeing
1. Crutch, Lehmann, et al., ‘Posterior cortical atrophy’.
2. Pratchett, Shaking Hands with Death, p.31.
3. Sacks, The Mind’s Eye, p.19.
4. Crutch, Schott, et al., ‘Shining a light on posterior cortical atrophy’.
5. Whitlock, Sutherland, et al., ‘Navigating from hippocampus to parietal cortex’.
6. Breveglieri, Hadjidimitrakis, et al., ‘Eye position encoding in three-dimensional space’.
Chapter 18: Between the Devil and the Deep Blue Sea
1. Ariga, ‘Common mechanisms of onset of cancer and neurodegenerative diseases’.
2. Staropoli, ‘Tumorigenesis and neurodegeneration’.
3. J. Altman, ‘Two faces of evil: cancer and neurodegeneration’, Alzforum, http://www.alzforum.org/news/conference-coverage/two-faces-evil-cancer-and-neurodegeneration
4. Cramer, Cirrito, et al., ‘ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models’.
5. Stamps, Bartoshuk, Heilman, ‘A brief olfactory test for Alzheimer’s disease’.
6. Wang, ‘Alzheimer’s families clamor for drug’.
7. Pierrot, Lhommel, et al., ‘Targretin improves cognitive and biological marker
s in a patient with Alzheimer’s disease’.
8. Shen, ‘Studies cast doubt on cancer drug as Alzheimer’s treatment’.
Chapter 19: To the Ends of the Earth
1. Salvor Nordal, of the University of Iceland, quoted in E. J. Kirby, ‘Iceland’s DNA: The world’s most precious genes?’ BBC, 2014, http://www.bbc.co.uk/news/magazine-27903831
2. Smiley, The Sagas of the Icelanders.
3. Jonsson, Atwal, et al., ‘A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline’.
4. Power, Steinberg, et al., ‘Polygenic risk scores for schizophrenia and bipolar disorder predict creativity’.
5. K. W. Burton, ‘Anti-Alzheimer’s gene may have led to the rise of grandparents’, Science, http://www.sciencemag.org/news/2015/11/anti-alzheimer-s-gene-may-have-led-rise-grandparents
6. Vassar, ‘BACE1 inhibitor drugs in clinical trials for Alzheimer’s disease’.
7. Cummings, Morstorf, Zhong, ‘Alzheimer’s disease drug-development pipeline’.
8. Derek Lowe in M. Burke, ‘Why Alzheimer’s drugs keep failing’, Scientific American, https://www.scientificamerican.com/article/why-alzheimer-s-drugs-keep-failing/
Chapter 20: Insights from India
1. Chandra, Ganguli, Ratcliff, et al., ‘Studies of the epidemiology of dementia’.
2. Hendrie, Osuntokun, et al., ‘Prevalence of Alzheimer’s disease and dementia in two communities’.
3. Hendrie, Hall, et al., ‘Alzheimer’s disease is rare in Cree’.
4. White, Petrovitch, et al., ‘Prevalence of dementia in older Japanese-American men in Hawaii’.
5. Ono, Hasegawa, et al., ‘Curcumin has potent anti-amyloidogenic effects for Alzheimer’s beta-amyloid fibrils in vitro’.
6. F. Yang, Lim, et al., ‘Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo’.
7. Belviranli, Okudan, et al., ‘Curcumin improves spatial memory and decreases oxidative damage in aged female rats’.
8. Baum, Lam, et al., ‘Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease’.
9. M. Taylor, Moore, et al., ‘Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer’s Aβ peptide’.
10. Popper, The Logic of Scientific Discovery, p. 316.
Chapter 21: Clues from Colombia
1. Lemere, Lopera, et al., ‘The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology’.
2. Sepulveda-Falla, Glatzel, Lopera, ‘Phenotypic profile of early-onset familial Alzheimer’s disease caused by presenilin-1 E280A mutation’.
3. Belluck, ‘Alzheimer’s Stalks a Colombian Family’.
Chapter 22: Alzheimer’s Legacy
1. Brookmeyer, Johnson, et al., ‘Forecasting the global burden of Alzheimer’s disease’.
2. Zissimopoulos, Crimmins, St Clair, ‘The value of delaying Alzheimer’s disease onset’.
3. De Strooper and Karran, ‘The cellular phase of Alzheimer’s disease’.
4. Kallo, Emri, et al., ‘Changes in the chemical barrier composition of tears in Alzheimer’s disease reveal potential tear diagnostic biomarkers’.
5. Kaiser, ‘What does a disease deserve?’
6. Herper, ‘The coming boom in brain medicines’.
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