DMT: The Spirit Molecule: A Doctor's Revolutionary Research into the Biology of Near-Death and Mystical Experiences

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DMT: The Spirit Molecule: A Doctor's Revolutionary Research into the Biology of Near-Death and Mystical Experiences Page 32

by Rick Strassman M. D.


  It took a few tries to find a suitable Buddhist community. Once more, Jim Fadiman at Stanford pointed me in the right direction, this time to a midwestern United States Zen monastery run by a rather reclusive, but startlingly solid, Asian teacher. I attended two weekend meditation retreats there in 1974 and felt as if I had arrived home. The monks were serene but down to earth, and we enjoyed being with each other. Most interesting was that most of them had gained their first view of the spiritual path while on psychedelic drugs.

  They did not volunteer this information, of course. But in the freewheeling early days of the temple, such informal self-disclosure was common. It was as simple as asking, “Did you take psychedelics before becoming a monk? How important were they in your decision?” The overwhelming majority had taken them and had experienced their first glimpse of the enlightened state of mind with their assistance.

  A five-week retreat at the monastery during a break from medical school helped me develop a portable and efficient Buddhist practice. The meditation was straightforward: sit comfortably, back straight, and just sit. “Just sit” as in “just walk,” “just wash the dishes,” “just breathe.” In other words, focus all your attention on the task at hand. When sitting, therefore, you just sat. No thinking, daydreaming, fidgeting, emotional reactions, talking, or whatever else complicated the sitting process. The regular in-and-out movement of the breath functioned as an excellent anchor, a point upon which the wandering mind could ground and focus its attention whenever distracting thoughts or feelings interrupted uncluttered awareness.

  Upon returning to medical school, I reserved a room for lunchtime meditation and there were always one or two people joining me for a halfhour “sit.” I stayed in close touch with several monks, visited the monastery regularly, and hosted a retreat led by priests traveling to New York.

  Buddhism and meditation also seemed a rich field of academic study. I arranged to take a medical school summer elective for mental health professionals at the Nyingma Institute, which had been established by a Tibetan Buddhist lama in the hills of Berkeley, California. During this course we learned the basic principles and practices of Buddhist psychology. It was here that I first learned about the Abhidharma, the Buddhist system of psychology.

  Abhidharma roughly translates into “catalog of mental states.” There are hundreds of Abhidharma texts, but the Nyingma lama was interested in sharing with us only the most basic principles.

  One fundamental tenet was that the normal flow of personal experience actually was a smooth synthesis of several component parts. These facets are called the skandhas, or “heaps,” the five “things” that make up our conscious state: form, feeling, perception, consciousness, and habitual tendencies. We spent days discussing each of these until we developed a consensus definition with which we felt comfortable and could express in familiar Western terms.

  Another important point was the possibility of, and methods for, dissolving the glue that held these skandhas together. By deconstructing, as it were, the facade of our sense of self, Buddhists believe we can access deeper layers of reality, compassion, love, and wisdom. There was a sequence of stages in that process, and a knowledgeable teacher could help the meditator recognize and progress through those steps. Buddhism had refined these techniques over millennia, and millions of practitioners had verified and validated these methods and their results.

  While these meditations were more elaborate and complicated than “just sitting,” they were fascinating, and they produced the promised results. I needed to write a scientific article on my summer experience, and I used that opportunity to publish a description of the Abhidharma system and some of my own meditative experiences. Learning about Abhidharma also got me thinking about its usefulness in measuring psychedelic states.1

  Upon graduating from medical school, I returned to California for psychiatric training. There, in Sacramento, I helped establish and administer a monastery-affiliated meditation group that met weekly and sponsored retreats led by monks. For years the group met in my house, and I had many opportunities to discuss my interests, psychedelic and otherwise, with members of the monastic community. At the monastery, I underwent a layperson’s ordination into the Buddhist sect whose teachings the abbot followed, and I maintained close ties with my original monk friends, who now were becoming senior members of the priestly hierarchy.

  Career and training opportunities drew me away from Sacramento after my four-year psychiatric residency at the University of California in Davis, but I returned two and a half years later to join their faculty. The local meditation group I helped establish still met, but the parent organization’s structure had changed substantially. Many monks had left the fold as the teachings became increasingly focused on the teacher himself and his spiritual experiences. At the same time the abbot was becoming more reclusive, surrounding himself with trusted assistants. In addition, there now existed a hierarchy within the lay community. The atmosphere had taken a turn toward “who is in, and who is out.” The informal and relaxed give-and-take no longer existed.

  When I later moved to New Mexico, I considered myself loosely affiliated with the monastery’s extended Buddhist community. I was not inclined to deal with the political structure now necessary to start a local meditation group, but I did seek out other local members and I meditated with them regularly in an informal setting. In addition, I remained in regular contact with several monks at the head temple, many of whom were now twenty-year acquaintances. While the monastic community as a whole had lost some of its luster, I considered it my spiritual home and was married there in 1990.

  There are many ways my Buddhist training and practice affected the DMT research. One of these was in how we supervised volunteers’ encounters with DMT.

  Supervising psychedelic sessions usually is called “sitting.” Many believe this comes from the idea of “babysitting” people who are in a highly dependent, at times confused and vulnerable state. Even more importantly, though, is “sitting” in the meditational sense. The research nurse, either Cindy or Laura, and I did our best to practice “just sitting” while being with our volunteers: watching the breath, being alert, eyes gazing straight ahead, ready to respond, keeping a positive and aware attitude, letting the research subject’s experience unfold without unnecessary interference.2

  My understanding of meditation also helped me guide people through the stages of the DMT experience. For example, I applied the Abhidharma’s model of mind when coaching volunteers not to get swept away by the onslaught of colors, or to investigate the space within the grains of wood in the door if they kept their eyes open. Suggesting volunteers let go, focus on the breath and body sensations, keep an open but fluid mind to whatever came their way—all of these were tools I had acquired during decades of meditation practice and study.

  Another example of how psychedelics and Buddhist meditation met was in the development of our rating scale.

  Previous paper-and-pencil psychological questionnaires that measured psychedelic drug effects had serious shortcomings. They assumed that psychedelics were “psychotomimetic” or “schizotoxic,” and therefore they emphasized unpleasant experiences. Many of these scales were developed using volunteers, sometimes ex-narcotic-addict prisoners, who were not told what drugs they were given, or what the effects might be.

  To offer an alternative to these tools for measuring the psychedelic experience, I used an Abhidharma- and skandha-based method of characterizing mental states. This purely descriptive model meshed well with what’s known as the “mental-status” approach to interviewing psychiatric patients: You talk with someone and gently investigate the quality of their basic mental functions, such as mood, thinking, and perceptions.

  The familiar Abhidharma terms “form,” “feeling,” “perception,” “consciousness,” and “habitual tendencies” became the framework or structure within which the rating scale’s questions emerged, and how we classified replies to those questions. However, instead of callin
g them skandhas, “clinical clusters” seemed more appropriate and palatable for a Western scientific audience.

  We gave and analyzed this new questionnaire, the Hallucinogen Rating Scale, or HRS, at the end of every DMT session for the entire project. The results were remarkable.

  It is well-known in clinical psychopharmacology that a good questionnaire is more sensitive than any biological factor in assessing drug effects. In other words, a well-designed rating scale is better than measurements of blood pressure, heart rate, or hormone levels in distinguishing doses of a drug, or different types of drugs, from each other. I hoped that the HRS would follow in that tradition, and this it did without difficulty. We were better able to separate responses to various doses of DMT, or the effects of combining DMT with other drugs, using HRS scores than by measuring changes in any biological variable, including all the cardiovascular and blood hormone data. However, it also validated the wisdom and strength of the Buddhist approach to mental states.

  Clifford Qualls, Ph.D., the Research Center biostatistician, and I grouped together HRS questions using the “clinical cluster” or skandha method and compared this method of analysis to a large number of alternative purely statistical models. The Abhidharma’s technique was as good as, if not superior to, ones developed solely upon mathematical considerations. Since the computer-derived classification of results was no better than the clinical cluster one, and since using the skandhas made more sense intuitively, the Buddhist classification system won out. Other groups have since used the HRS and confirmed its usefulness in measuring other altered states of consciousness, drug-induced and otherwise.3

  Buddhism also helped me make sense of people’s DMT sessions. Its far-reaching perspective includes all experiences: spiritual, near-death, and even nonmaterial or invisible realms. However, I did come up against two serious limitations in my lack of Buddhist education.

  How was I to respond to a volunteer who spoke as if she or he just had undergone a drug-induced spiritual experience? Was it a “real” enlightenment or not? As detailed in chapter 16, “Mystical States,” these sessions certainly left me feeling as if something deeply profound had happened. And there was no question on the volunteers’ part that they had undergone the deepest and most profound experience of their lives. However, it was beyond my training and expertise to determine the validity or “certifiability” of a volunteer’s understanding with anything other than psychiatric models of interpretation.

  Another problem was how to relate what I knew about Buddhist approaches to nonmaterial beings with what our volunteers were reporting. For example, Tibetan and Japanese versions of Buddhism possess a full roster of demons, gods, and angels. I understood these encounters to symbolically represent certain qualities of ourselves, not autonomous noncorporeal life forms.

  When volunteers began reporting contact, my first reaction was, “Oh, this is something they talk about in Buddhism. They are just aspects of our own minds.”

  These encounters got stranger, however, and the beings started testing, probing, inserting things into, eating, and raping our volunteers. A Buddhist framework seemed less capable of explaining these types of experiences. Generically I could apply the inherent skepticism of Buddhism in taking anything as “real” or “special” about these stories. That is, it was “just meeting beings.” These apparent life forms were not necessarily any wiser or more trustworthy than anything else we might meet in our lives or minds.

  Nevertheless, I needed some guidance, both for the spiritual experience and the “contact” aspects of our work. I began sharing our findings, and my questions, with trusted monk friends. The one to whom I turned most often was Venerable Margaret, a Buddhist priest I met in 1974 during my first stay at the monastery.4

  A clinical psychologist by training, Margaret became a Buddhist monk after realizing, “I didn’t want to be let loose on the world the way I was.” She wanted to experience her own mental and spiritual health before trying to help others. She loved monastic life, however, and stayed on. Margaret and I spoke the same language, shared the same concerns, and viewed the human condition through similarly trained clinical eyes.

  Before beginning the actual DMT studies, I happened to spend a few days at the monastery. My two-year journey through the regulatory labyrinth, seeking permission and funding to begin giving DMT, was drawing to a close. Margaret had risen to chief assistant to the abbot, and her time was heavily scheduled. However, we found an opportunity to meet and I updated her on my personal and professional life. The conversation moved into my interest in giving DMT to human research subjects. Sharing with her my belief that the pineal gland might make DMT at mystical moments in our lives, I speculated about its possible role in death and near-death states.

  The lanky and shaven-headed woman monk touched the tips of her fingers together in front of her mouth, tenting them in and out. Her intensely blue eyes narrowed, and she looked over my shoulder, meeting the white wall with her gaze.

  She said quietly, “What you are suggesting is something that only one out of a million people could do.”

  I took this intentionally unclear remark as encouragement to go deeper with the topic. Wondering about the role of psychedelics in spiritual development, I commented on how many of the now-senior monks had gotten their first sighting of the spiritual path from LSD and other drugs.

  Margaret laughed, saying, “You know, I honestly can’t say if my LSD trips helped or hurt my spiritual practice!”

  “Hard to tell, isn’t it?” I replied.

  “Indeed.”

  She looked at her watch, picked up her tea cup, and graciously excused herself.

  The next year, 1990, I was married at the monastery. At separate meetings before the ceremony, I chatted with two other monk friends, now some of the highest ranking officers in the order. Both of them had taken psychedelic drugs in college with a fellow who later became a close friend of mine in New Mexico. This mutual acquaintance was well-known for using MDMA in a psychotherapeutic setting. They both asked about their friend and his MDMA research and were in kind fascinated by my plans to study DMT.

  After wrapping up the dose-response study in 1992, I wrote a long letter to Margaret describing the full range of the stories volunteers shared with us, including near-death, enlightenment, and being contact. I also shared with her my feelings that the setting was too neutral, and our volunteers too familiar with psychedelics, for any real beneficial effects to result. I raised the issue of helping people more directly, along the lines of a psilocybin-assisted psychotherapy project with the terminally ill.

  I was drawn to a terminal illness study because of the promising work in this area performed during the first wave of psychedelic clinical research in the 1960s. In addition, its emphasis on the positive effects of spiritual and near-death experiences possible with psychedelics appealed to my deeper interest in these drugs.

  Margaret replied, “Most interesting! But to what purpose? Maybe future ‘helping’ work will shed some light on that.” She also wondered about the risk-to-benefit ratio and advised performing such a study only if I was sure there were extremely few risks and an equally high likelihood of success. Insightfully, she also asked me to consider the lack of time available to undo any harm incurred from a painful or disturbing psilocybin session.

  The years passed quickly, and by the end of 1994 my questions grew regarding the utility of my psychedelic research. Adverse effects accumulated, and long-term benefit was difficult to assess. In addition, the constant exposure to psychedelicized volunteers was beginning to exhaust me. I shared these developments with Margaret.

  As always, she supported whatever seemed most useful for my own spiritual growth. If it involved giving up the research, she understood. However, she encouraged me to look for someone to whom I might transfer the project so the work I had begun would not end in my absence.

  The additional circumstances described in the last chapter led to my moving to Canada, but I commuted to Al
buquerque in order to continue running studies. After relocating, I met the members of the local monastery- affiliated meditation group and started sitting with them. There existed a major branch of the order in a nearby U.S. state across the border, and their priest scheduled a retreat in our community. Venerable Gwendolyn arrived, and the weekend workshop began.

  Gwendolyn had entered the head temple directly from her parents’ home. She had had a series of extraordinarily profound spiritual experiences at the monastery and was a highly ranked teacher. Nevertheless, she was not especially wise in the ways of the world, and running an urban meditation center was a significant challenge to her social skills.

  During a pastoral counseling session with Gwendolyn, I let her know of the New Mexico research and some of my growing ambivalence toward it. I appreciated the opportunity to air my story to a monk who knew nothing about me, and to listen to her fresh perspective.

  I was surprised to hear Gwendolyn’s voice on the phone a week later.

  “I was sick for three days after talking with you, it upset me so. I called the abbot, who as you know is near death. This is the first issue he’s taken a personal interest in for over a year. He and I talked, as I did with other senior monks. We have decided you must stop your research immediately. I’ll write you this week a more formal letter.”

  I replied, “Let me think about it.”

  Two weeks later, a letter came, not from Gwendolyn, but from Margaret. It began with, “I hope what I heard third-hand isn’t true. But if it is, let me say this.” With that introduction, she began an indictment of my research: past, present, and planned:

  “Your psychedelic research is ultimately futile, devoid of real benefit to humanity, and dangerous;

 

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