"Well," replied Thorndyke, "let us set out the argument and trace the connections. The starting-point was the aluminium case that Mr. Rabbage brought us. Those tubes of fleas and lice were clearly an abnormal phenomenon. They might, as you suggested, have belonged to a scientific collector; but that was not probable. The fleas were alive, and were meant to remain alive, as the perforated caps of the tubes proved,' And the lice had merely died, as lice quickly do if they are not fed. They did not appear to have been killed, But against your view there were two very striking facts, one of which I fancy you did not observe. The fleas were not the common human flea; they were Asiatic rat-fleas."
"You are quite right," I admitted. "I did not notice that."
"Then," he continued, "there was the aniseed with which the parchment caps of the tubes were scented. Now aniseed is irresistible to rats. It is an infallible bait. But it is not specially attractive to fleas. What then was the purpose of the scent? The answer, fantastic as it was, had to be provisionally accepted because it was the only one that suggested itself. If one of these tubes had been exposed to rats—dropped down a rat-hole, for instance—it is certain that the rats would have gnawed off the parchment cap. Then the fleas would have been liberated, and as they were rat-fleas, they would have immediately fastened upon the rats. The tubes, therefore, appeared to be an apparatus for disseminating rat-fleas.
"But why should anyone want to disseminate rat-fleas? That question at once brought into view another striking fact, Here, in these tubes, were rat-fleas and body-lice: both carriers of deadly disease. The rat-flea is a carrier of plague; the body-louse is a carrier of typhus. It was an impressive coincidence. It suggested that the dissemination of rat-fleas might be really the dissemination of plague; and if the lice were distributed, too, that might mean the distribution of typhus.
"And now consider the maps. The circles on them all marked old slum-areas tenanted by low-class aliens. But old slums abound in rats; and low-class aliens abound in body-lice. Here was another coincidence. Then there was the note-tablet bearing numbers associated with the letters a and b and plus and minus signs. The letters a and b might mean rat and louse or plague and typhus, and the plus and minus might mean a success or a failure to produce an outbreak of disease. That was merely speculative, but it was quite consistent.
"So far we were dealing with a hypothesis based on simple observation. But that hypothesis could be proved or disproved. The question was: Were these insects infected insects, or were they not? To settle this I took one flea from each of the four tubes and 'sowed' it on agar, with the result that from each flea I got a typical culture of plague bacillus, which I verified with Haffkine's 'Stalactite test.' I also examined one louse from each of the two tubes, and in each case got a definite typhus reaction. So the insects were infected and the hypothesis was confirmed.
"The next thing was to find the owner of the tubes, Now the circles on the maps indicated some sort of activity, presumably connected with rats and carried on in these areas. I visited those areas and got into conversation with the inhabitants on the subject of rats, rat-catchers, rat pits, sewermen, and everything bearing on rats; and at length I heard of an exhibitor of performing rats. You know the rest. We found the man, we observe that all his rats, excepting the tame white ones, were black rats—the special plague-carrying species—and we found on this spot a dead rat, which, I ascertained on examining the body, had died of plague. Finally there was Polton's little book giving us the finger prints of the owner of the aluminium case. That completed the identification; and inquiries at the Local Government Board showed that cases of plague and typhus had occurred in the marked areas."
"Had not the authorities taken any steps in the matter?" I asked.
"Oh, yes," he replied. "They had carried out an energetic rat campaign in the London Docks, the likeliest source of infection. Naturally, they would not think of a criminal lunatic industriously sowing plague broad cast."
"Then how did you connect this man with the bank outrage?"
"I never did, very conclusively," he replied. "It was mostly a matter of inference. You see, the two crimes were essentially similar. They were varieties of the same type. Both were cases of idiotic destructiveness, and the agent in each was evidently a moral imbecile who was a professed enemy of society. Such persons are rare in this country, and when they occur are usually foreigners, most commonly Russians, or East Europeans of some kind. The only actual clue was the date on Pilcher's letter, the rather peculiar figures of which were extraordinarily like those on the maps and the note-tablet. Still, it was little more than a guess, though it happens to have turned out correct."
"And how do you suppose this fellow avoided getting plague and typhus himself?"
"It was quite likely that he had had both. But he could easily avoid the typhus by keeping himself clean and his clothing disinfected; and as to the plague, he could have used Haffkine's plague-prophylactic and given it to the woman. Clearly it would not have suited him to have a case of plague in the house and have the health officer inspecting the premises."
That was the end of the case, unless I should include in the history a very handsome fee sent to my colleague by the President of the Local Government Board.
"I think we have earned it," said Thorndyke; "and yet I am not sure that Mr. Rabbage is not entitled to a share."
And in fact, when that benevolent person called a few days later to receive a slightly ambiguous report and tender his fee, he departed beaming, bearing a donation wherewith to endow an additional bed, cot, or basket, in the St. Francis Home of Rest.
Rex v. Burnaby
It is a normal incident in general medical practice that the family doctor soon drifts into the position of a family friend. The Burnabys had been among my earliest patients, and mutual sympathies had quickly brought about the more intimate relationship. It was a pleasant household, pervaded by a quiet geniality and a particularly attractive homely, unaffected culture. It was an interesting household, too, for the disparity in age between the husband and wife made the domestic conditions a little unusual and invited speculative observation. And there were other matters, to be referred to presently.
Frank Burnaby was a somewhat delicate man of about fifty: quiet, rather shy, gentle, kindly, and singularly innocent and trustful. He held a post at the Records Office, and was full of quaint and curious lore derive from the ancient documents on which he worked: selections from which he would retail in the family circle with a picturesque imagination and a fund of quiet, dry humour that made them delightful to listen to. I have never met a more attractive man, or one whom I liked better or respected more.
Equally attractive, in an entirely different way, was his wife: an extremely charming and really beautiful woman of under thirty—little more than a girl, in fact: amiable, high-spirited and full of fun and frolic, but nevertheless an accomplished, cultivated woman with a strong interest in her husband's pursuits. They appeared to me an exceedingly happy and united couple deeply attached to one another and in perfect sympathy. There were four children—three boys and a girl—of Burnaby's by his first wife; and their devotion to their young stepmother spoke volumes for her care of them.
But there was a fly in the domestic ointment: at least, that was what I felt. There was another family friend, a youngish man named Cyril Parker.
Not that I had anything against him, personally, but I was not quite happy about the relationship. He was a markedly good-looking man, pleasant, witty, and extremely well informed; for he was a partner in a publishing house and acted as reader for the firm; whence it happened that he, like Mr. Burnaby, gathered stores of interesting matter from his professional reading. But I could not disguise from myself that his admiration and affection for Mrs. Burnaby were definitely inside the danger zone, and that the intimacy—on his side, at any rate—was growing rather ominously. On her side there seemed nothing more than frank, though very pronounced, friendship. But I looked at the relationship askance. She was
a woman whom any man might have fallen in love with, and I did not like the expression that I sometimes detected in Parker's eyes when he was looking at her. Still, there was nothing in the conduct of either to which the slightest exception could have been taken or which in any way foreshadowed the terrible disaster which was so shortly to befall.
The starting-point of the tragedy was a comparatively trivial event. By much poring over crabbed manuscripts, Mr. Burnaby developed symptoms of eye-strain which caused me to send him to an oculist for an opinion and a prescription for suitable spectacles. On the evening of the day on which he had consulted the oculist, I received an urgent summons from Mrs. Burnaby, and, on arriving at the house, found her husband somewhat seriously ill. His symptoms were rather puzzling, for they corresponded to no known disease. His face was flushed, his temperature slightly raised, his pulse rapid, though the breathing was slow, his throat was excessively dry, and his pupils widely dilated. It was an extraordinary condition, resembling nothing within my knowledge excepting atropine poisoning.
"Has he been taking medicine of any kind?" I asked.
Mrs. Burnaby shook her head. "He never takes any drugs or medicine but what you prescribe; and it couldn't be anything that he has taken, because the attack came on quite soon after he came home, before he had either food or drink."
It was very mysterious and the patient himself could throw no light on the origin of the attack. While I was reflecting on the matter, I happened to glance at the mantelpiece, on which I noticed a drop bottle labelled "The Eye Drops" and a prescription envelope. Opening the latter I found the oculist's prescription for the drops—a very weak solution of atropine sulphate.
"Has he had any of these drops?" I asked.
"Yes," replied Mrs. Burnaby. "I dropped some into his eyes as soon as he came in; two drops in each eye, according to the directions."
It was very odd. The amount of atropine in those four drops was less than a hundredth of a grain; an impossibly small dose to produce the symptoms.
Yet he had all the appearance of having taken a poisonous dose, which he obviously had not, since the drop-bottle was nearly full. I could make nothing of it. However, I treated it as a case of atropine poisoning; and as the treatment produced marked improvement, I went home, more mystified than ever.
When I called on the following morning, I learned that he was practically well, and had gone to his office. But that evening I had another urgent message, and on hurrying round to Burnaby's house, found him suffering from an attack similar to, but even more severe than, the one on the previous day. I immediately administered an injection of pilocarpine and other appropriate remedies, and had the satisfaction of seeing a rapid improvement in his condition. But whereas the efficacy of the treatment proved that the symptoms were really due to atropine, no atropine appeared to have been taken excepting the minute quantity contained in the eye-drops.
It was very mysterious. The most exhaustive inquiries failed to suggest any possible source of the poison excepting the drops; and as each attack had occurred a short time after the use of them, it was impossible to ignore the apparent connection, in spite of the absurdly minute dose.
"I can only suppose," said I, addressing Mrs. Burnaby and Mr. Parker, who had called to make inquiries, "that Burnaby is the subject of an idiosyncrasy—that he is abnormally sensitive to this drug."
"Is that a known condition?" asked Parker.
"Oh, yes," I replied. "People vary enormously in the way in which they react to drugs. Some are so intolerant of particular drugs—iodine, for instance—that ordinary medicinal doses produce poisonous effects, while others have the most extraordinary tolerance. Christisori, in his Treatise on Poisons, gives a case of a man, unaccustomed to opium, who took nearly an ounce of laudanum without any effect—a dose that would have killed an ordinary man. These drugs are terrible pitfalls for the doctor who doesn't know his patient. Just think what might have happened to Burnaby if someone had given him a full medicinal dose of belladonna."
"Does belladonna have the same effect as atropine?" asked Mrs. Burnaby.
"It is the same," I replied. "Atropine is the active principle of belladonna."
"What a mercy," she exclaimed, "that we discovered this idiosyncrasy in time. I suppose he had better discontinue the drops?"
"Yes," I answered, "most emphatically; and I will write to Mr. Haines and let him know that the atropine is impracticable."
I accordingly wrote to the oculist, who was politely sceptical as to the connection between the drops and the attacks. However, Burnaby settled the matter by refusing point-blank to have any further dealings with atropine; and his decision was so far justified that, for the time being, the attacks did not recur.
A couple of months passed. The incident had, to a great extent, faded from my mind. But then it was revived in a way that not only filled me with astonishment but caused me very grave anxiety. I was just about to set out on my morning round when Burnaby's housemaid met me at my door, breathing quickly and carrying a note. It was from Mrs. Burnaby, begging me to call at once and telling me that her husband had been seized by an attack similar to the previous ones. I ran back for my emergency bag and then hurried round to the house, where I found Burnaby lying on a sofa, very flushed, rather alarmed, and exhibiting well-marked symptoms of atropine poisoning. The attack, however, was not a very severe one, and the application of the appropriate remedies soon produced a change for the better.
"Now, Burnaby," I said, as he sat up with a sigh of relief. "what have you been up to? Haven't been tinkering with those drops again?"
"No," he replied. "Why should I? Haines has finished with my eyes."
"Well, you've been taking something with atropine in it."
"I suppose I have, but I can't imagine what. I have had no medicine of any kind."
"No pills, lozenges, liniment, plaster, or ointment?"
"Nothing medicinal of any sort," he replied. "In fact, I have swallowed nothing to-day but my breakfast; and the attack came on directly after, though it was a simple enough meal, goodness knows—just a couple of pigeon's eggs and some toast and tea."
"Pigeon's eggs," said I, with a grin, "why not sparrow's?"
"Cyril sent them—as a joke, I think," Mrs. Burnaby explained (Cyril, of course, was Mr. Parker), "but I must say Frank enjoyed them. You see, Cyril has taken lately to keeping pigeons and rabbits and other edible beasts, and I think he has done it principally for Frank's sake, as you have ordered him a special diet. We are constantly getting things from Cyril now—pigeons and rabbits especially; and much younger than we can buy them at the shops."
"Yes," said Burnaby, "he is most generous. I should think he supplies more than half my diet. I hardly like to accept so much from him."
"It gives him pleasure to send these gifts," said Mrs. Burnaby; "but I wish it gave him pleasure to slaughter the creatures first. He always brings or sends them alive, and the cook hates killing them. As to me, I couldn't do it, though I deal with the corpses afterwards. I prepare nearly all Frank's food myself."
"Yes," said Burnaby, with a glance of deep affection at his wife,
"Margaret is an artist in kickshaws and I consume the works of art. I can tell you, doctor, I live like a fighting cock."
This was all very well, but it was beside the question; which was, where did the atropine come from? If Burnaby had swallowed nothing but his breakfast, it would seem that the atropine must have been in that. I pointed this out.
"But you know, doctor," said Burnaby, "that isn't possible. We can write the eggs off. You can't get poison into an egg without making a hole in the shell, and these eggs were intact. And as to the bread and butter, and the tea, we all had the same, and none of the others seem any the worse."
"That isn't very conclusive," said I. "A dose of atropine that would be poisonous to you would probably have no appreciable effect on the others. But, of course, the real mystery is how on earth atropine could have got into any of the food."
> "It couldn't," said Burnaby and that really was my own conviction. But it was an unsatisfactory conclusion, for it left the mystery unexplained; and when a length I took my leave, to continue my rounds of visits, it was with the uncomfortable feeling that I had failed to trace the origin of the danger or to secure my patient against its recurrence.
Nor was my uneasiness unjustified. Little more than a week had passed when a fresh summons brought me to Burnaby's house, full of bewilderment and apprehension. And indeed there was good cause for apprehension; for when I arrived, to find Burnaby lying speechless and sightless, his blue eyes turned to blank discs of black, glittering with the unnatural "belladonna sparkle,"—when I felt his racing pulse and watched his vain efforts to swallow a sip of water,—I began to ask myself whether he was not beyond recall. The same question was asked mutely by the terrified eyes of his wife, who rose like a ghost from his bedside as I entered the room. But once more he responded to the remedies, though more slowly this time, and at the end of an hour I was relieved to see that the urgent danger was past, although he still remained very ill.
Meanwhile, inquiries failed utterly to elicit any explanation of the attack. The symptoms had set in shortly after dinner; a simple meal, consisting of a pigeon cooked en casserole by Mrs. Burnaby herself, vegetables and a light pudding which had been shared by the rest of the family, and a little Chablis from a bottle that had been unsealed and opened in the dining-room. Nothing else had been taken and no medicaments of any kind used. On the other hand, any doubts as to the nature of the attack were set at rest by a chemical test made by me and confirmed by the Clinical Research Association. Atropine was demonstrably present, though the amount was comparatively small. But its source remained an impenetrable mystery.
It was a profoundly disturbing state of affairs. The last attack had narrowly missed a fatal termination and the poison was still untraced.
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