Couet C, Delarue J, Ritz P, Antoine JM, Lamisse F. Effect of dietary fish oil on body fat mass and basal fat oxidation in healthy adults. Int J Obes Relat Metab Disord. 1997;21(8):637-643.
Buckley JD, Howe PRC. Anti-obesity effects of long-chain omega-3 polyunsaturated fatty acids. Obes Rev. 2009;10(6):648-659. doi:10.1111/j.1467-789X.2009.00584.x.
Smith GI, Atherton P, Reeds DN, et al. Omega-3 polyunsaturated fatty acids augment the muscle protein anabolic response to hyperinsulinaemia–hyperaminoacidaemia in healthy young and middle-aged men and women. Clin Sci. 2011;121(6):267-278. doi:10.1042/CS20100597.
Ponnampalam EN, Mann NJ, Sinclair AJ. Effect of feeding systems on omega-3 fatty acids, conjugated linoleic acid and trans fatty acids in Australian beef cuts: potential impact on human health. Asia Pac J Clin Nutr. 2006;15(1):21-29.
Poudyal H, Panchal SK, Diwan V, Brown L. Omega-3 fatty acids and metabolic syndrome: Effects and emerging mechanisms of action. Prog Lipid Res. 2011;50(4):372-387. doi:10.1016/j.plipres.2011.06.003.
Rosell MS, Lloyd-Wright Z, Appleby PN, Sanders TA, Allen NE, Key TJ. Long-chain n–3 polyunsaturated fatty acids in plasma in British meat-eating, vegetarian, and vegan men. Am J Clin Nutr. 2005;82(2):327-334. doi:10.1093/ajcn/82.2.327.
Dyerberg J, Madsen P, Møller JM, Aardestrup I, Schmidt EB. Bioavailability of marine n-3 fatty acid formulations. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 2010;83(3):137-141. doi:10.1016/j.plefa.2010.06.007.
Neubronner J, Schuchardt JP, Kressel G, Merkel M, von Schacky C, Hahn A. Enhanced increase of omega-3 index in response to long-term n-3 fatty acid supplementation from triacylglycerides versus ethyl esters. Eur J Clin Nutr. 2011;65(2):247-254. doi:10.1038/ejcn.2010.239.
Dyerberg J, Bang HO. Haemostatic function and platelet polyunsaturated fatty acids in Eskimos. Lancet. 1979;2(8140):433-435.
WebMD. Lovaza. WebMD Website. https://www.webmd.com/drugs/2/drug-148529/lovaza-oral/details. Accessed August 26, 2018.
Dyerberg J, Madsen P, Møller JM, Aardestrup I, Schmidt EB. Bioavailability of marine n-3 fatty acid formulations. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 2010;83(3):137-141. doi:10.1016/j.plefa.2010.06.007.
Song J-H, Inoue Y, Miyazawa T. Oxidative Stability of Docosahexaenoic Acid-containing Oils in the Form of Phospholipids, Triacylglycerols, and Ethyl Esters. Biosci Biotechnol Biochem. 1997;61(12):2085-2088. doi:10.1271/bbb.61.2085.
Holick MF. Vitamin D is essential to the modern indoor lifestyle. Science News Website. https://www.sciencenews.org/article/vitamin-d-essential-modern-indoor-lifestyle. October 8, 2010. Accessed August 26, 2018; Holick MF. Vitamin D: evolutionary, physiological and health perspectives. Curr Drug Targets. 2011;12(1):4-18.
Wacker M, Holick MF. Vitamin D - effects on skeletal and extraskeletal health and the need for supplementation. Nutrients. 2013;5(1):111-148. doi:10.3390/nu5010111.
Dawson-Hughes B, Mithal A, Bonjour J-P, et al. IOF position statement: vitamin D recommendations for older adults. Osteoporos Int. 2010;21(7):1151-1154. doi:10.1007/s00198-010-1285-3; Wang TJ, Pencina MJ, Booth SL, et al. Vitamin D Deficiency and Risk of Cardiovascular Disease. Circulation. 2008;117(4):503-511. doi:10.1161/CIRCULATIONAHA.107.706127; Pilz S, Dobnig H, Fischer JE, et al. Low Vitamin D Levels Predict Stroke in Patients Referred to Coronary Angiography. Stroke. 2008;39(9):2611-2613. doi:10.1161/STROKEAHA.107.513655; Giovannucci E. Epidemiological Evidence for Vitamin D and Colorectal Cancer. J Bone Miner Res. 2007;22(S2):V81-V85. doi:10.1359/jbmr.07s206; Hyppönen E, Läärä E, Reunanen A, Järvelin M-R, Virtanen SM. Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. Lancet. 2001;358(9292):1500-1503. doi:10.1016/S0140-6736(01)06580-1; Munger KL, Levin LI, Hollis BW, Howard NS, Ascherio A. Serum 25-Hydroxyvitamin D Levels and Risk of Multiple Sclerosis. JAMA. 2006;296(23):2832. doi:10.1001/jama.296.23.2832; Nnoaham KE, Clarke A. Low serum vitamin D levels and tuberculosis: a systematic review and meta-analysis. Int J Epidemiol. 2008;37(1):113-119. doi:10.1093/ije/dym247; Cannell JJ, Vieth R, Umhau JC, et al. Epidemic influenza and vitamin D. Epidemiol Infect. 2006;134(06):1129. doi:10.1017/S0950268806007175.
Holick MF. Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am J Clin Nutr. 2004;79(3):362-371. doi:10.1093/ajcn/79.3.362.
Terushkin V, Bender A, Psaty EL, Engelsen O, Wang SQ, Halpern AC. Estimated equivalency of vitamin D production from natural sun exposure versus oral vitamin D supplementation across seasons at two US latitudes. J Am Acad Dermatol. 2010;62(6):929.e1-929.e9. doi:10.1016/j.jaad.2009.07.028.
Cordain L, Eaton SB, Sebastian A, et al. Origins and evolution of the Western diet: health implications for the 21st century. Am J Clin Nutr. 2005;81(2):341-354. doi:10.1093/ajcn.81.2.341.
Blumberg JB, Frei BB, Fulgoni VL, Weaver CM, Zeisel SH, Zeisel SH. Impact of Frequency of Multi-Vitamin/Multi-Mineral Supplement Intake on Nutritional Adequacy and Nutrient Deficiencies in U.S. Adults. Nutrients. 2017;9(8). doi:10.3390/nu9080849.
Erkkilä AT, Booth SL. Vitamin K intake and atherosclerosis. Curr Opin Lipidol. 2008;19(1):39-42. doi:10.1097/MOL.0b013e3282f1c57f; Dawson-Hughes B, Mithal A, Bonjour J-P, et al. IOF position statement: vitamin D recommendations for older adults. Osteoporos Int. 2010;21(7):1151-1154. doi:10.1007/s00198-010-1285-3.
Schwalfenberg GK. Vitamins K1 and K2: The Emerging Group of Vitamins Required for Human Health. J Nutr Metab. 2017;2017:6254836. doi:10.1155/2017/6254836.
Miller ER, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med. 2005;142(1):37-46.
Onakpoya I, Hung SK, Perry R, Wider B, Ernst E. The Use of Garcinia Extract (Hydroxycitric Acid) as a Weight loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. J Obes. 2011;2011:1-9. doi:10.1155/2011/509038.
Onakpoya I, Terry R, Ernst E. The Use of Green Coffee Extract as a Weight Loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. Gastroenterol Res Pract. 2011;2011:1-6. doi:10.1155/2011/382852.
Watras AC, Buchholz AC, Close RN, Zhang Z, Schoeller DA. The role of conjugated linoleic acid in reducing body fat and preventing holiday weight gain. Int J Obes. 2007;31(3):481-487. doi:10.1038/sj.ijo.0803437; Joseph S V., Jacques H, Plourde M, Mitchell PL, McLeod RS, Jones PJH. Conjugated Linoleic Acid Supplementation for 8 Weeks Does Not Affect Body Composition, Lipid Profile, or Safety Biomarkers in Overweight, Hyperlipidemic Men. J Nutr. 2011;141(7):1286-1291. doi:10.3945/jn.110.135087; Risérus U, Vessby B, Ärnlöv J, Basu S. Effects of cis-9,trans-11 conjugated linoleic acid supplementation on insulin sensitivity, lipid peroxidation, and proinflammatory markers in obese men. Am J Clin Nutr. 2004;80(2):279-283. doi:10.1093/ajcn/80.2.279.
Morimoto C, Satoh Y, Hara M, Inoue S, Tsujita T, Okuda H. Anti-obese action of raspberry ketone. Life Sci. 2005;77(2):194-204. doi:10.1016/j.lfs.2004.12.029.
Doherty M, Smith PM. Effects of caffeine ingestion on rating of perceived exertion during and after exercise: a meta-analysis. Scand J Med Sci Sport. 2005;15(2):69-78. doi:10.1111/j.1600-0838.2005.00445.x.
Beck TW, Housh TJ, Schmidt RJ, et al. The Acute Effects of a Caffeine-Containing Supplement on Strength, Muscular Endurance, and Anaerobic Capabilities. J Strength Cond Res. 2006;20(3):506. doi:10.1519/18285.1.
Fett CA, Aquino NM, Schantz Junior J, Brandão CF, de Araújo Cavalcanti JD, Fett WC. Performance of muscle strength and fatigue tolerance in young trained women supplemented with caffeine. J Sports Med Phys Fitness. 2018;58(3):249-255. doi:10.23736/S0022-4707.17.06615-4.
Ri
chardson DL, Clarke ND. Effect of Coffee and Caffeine Ingestion on Resistance Exercise Performance. J Strength Cond Res. 2016;30(10):2892-2900. doi:10.1519/JSC.0000000000001382.
Astorino TA, Rohmann RL, Firth K. Effect of caffeine ingestion on one-repetition maximum muscular strength. Eur J Appl Physiol. 2007;102(2):127-132. doi:10.1007/s00421-007-0557-x.
Da Silva VL, Messias FR, Zanchi NE, Gerlinger-Romero F, Duncan MJ, Guimarães-Ferreira L. Effects of acute caffeine ingestion on resistance training performance and perceptual responses during repeated sets to failure. J Sports Med Phys Fitness. 2015;55(5):383-389.
Astrup A, Toubro S, Cannon S, Hein P, Breum L, Madsen J. Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers. Am J Clin Nutr. 1990;51(5):759-767. doi:10.1093/ajcn/51.5.759.
Mora-Rodríguez R, Pallarés JG, López-Samanes Á, Ortega JF, Fernández-Elías VE. Caffeine Ingestion Reverses the Circadian Rhythm Effects on Neuromuscular Performance in Highly Resistance-Trained Men. Bacurau RFP, ed. PLoS One. 2012;7(4):e33807. doi:10.1371/journal.pone.0033807.
Acheson KJ, Zahorska-Markiewicz B, Pittet P, Anantharaman K, Jéquier E. Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals. Am J Clin Nutr. 1980;33(5):989-997. doi:10.1093/ajcn/33.5.989; Koot P, Deurenberg P. Comparison of Changes in Energy Expenditure and Body Temperatures after Caffeine Consumption. Ann Nutr Metab. 1995;39(3):135-142. doi:10.1159/000177854.
Robertson D, Wade D, Workman R, Woosley RL, Oates JA. Tolerance to the humoral and hemodynamic effects of caffeine in man. J Clin Invest. 1981;67(4):1111-1117. doi:10.1172/JCI110124.
Ostojic SM. Yohimbine: The Effects on Body Composition and Exercise Performance in Soccer Players. Res Sport Med. 2006;14(4):289-299. doi:10.1080/15438620600987106; McCarty MF. Pre-exercise administration of yohimbine may enhance the efficacy of exercise training as a fat loss strategy by boosting lipolysis. Med Hypotheses. 2002;58(6):491-495.
Lefkowitz RJ. Direct binding studies of adrenergic receptors: biochemical, physiologic, and clinical implications. Ann Intern Med. 1979;91(3):450-458.
Strosberg AD. Structure, function, and regulation of adrenergic receptors. Protein Sci. 1993;2(8):1198-1209. doi:10.1002/pro.5560020802.
Manolopoulos KN, Karpe F, Frayn KN. Marked resistance of femoral adipose tissue blood flow and lipolysis to adrenaline in vivo. Diabetologia. 2012;55(11):3029-3037. doi:10.1007/s00125-012-2676-0.
Millan MJ, Newman-Tancredi A, Audinot V, et al. Agonist and antagonist actions of yohimbine as compared to fluparoxan at 2-adrenergic receptors (AR)s, serotonin (5-HT)1A, 5-HT1B, 5-HT1D and dopamine D2 and D3 receptors. Significance for the modulation of frontocortical monoaminergic transmission and depressive states. Synapse. 2000;35(2):79-95. doi:10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X.
Galitzky J, Taouis M, Berlan M, Rivière D, Garrigues M, Lafontan M. Alpha 2-antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male volunteers. Eur J Clin Invest. 1988;18(6):587-594.
Nelson BC, Putzbach K, Sharpless KE, Sander LC. Mass Spectrometric Determination of the Predominant Adrenergic Protoalkaloids in Bitter Orange (Citrus aurantium). J Agric Food Chem. 2007;55(24):9769-9775. doi:10.1021/jf072030s.
Haaz S, Fontaine KR, Cutter G, Limdi N, Perumean-Chaney S, Allison DB. Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update. Obes Rev. 2006;7(1):79-88. doi:10.1111/j.1467-789X.2006.00195.x; Gougeon R, Harrigan K, Tremblay J-F, Hedrei P, Lamarche M, Morais JA. Increase in the Thermic Effect of Food in Women by Adrenergic Amines Extracted from Citrus Aurantium. Obes Res. 2005;13(7):1187-1194. doi:10.1038/oby.2005.141.
Brown CM, McGrath JC, Midgley JM, et al. Activities of octopamine and synephrine stereoisomers on alpha-adrenoceptors. Br J Pharmacol. 1988;93(2):417-429.
Du M, Shen QW, Zhu MJ, Ford SP. Leucine stimulates mammalian target of rapamycin signaling in C2C12 myoblasts in part through inhibition of adenosine monophosphate-activated protein kinase. J Anim Sci. 2007;85(4):919-927. doi:10.2527/jas.2006-342; Doi M, Yamaoka I, Fukunaga T, Nakayama M. Isoleucine, a potent plasma glucose-lowering amino acid, stimulates glucose uptake in C2C12 myotubes. Biochem Biophys Res Commun. 2003;312(4):1111-1117.
Staten MA, Bier DM, Matthews DE. Regulation of valine metabolism in man: a stable isotope study. Am J Clin Nutr. 1984;40(6):1224-1234. doi:10.1093/ajcn/40.6.1224.
Calder PC. Branched-Chain Amino Acids and Immunity. J Nutr. 2006;136(1):288S-293S. doi:10.1093/jn/136.1.288S; Meeusen R, Watson P. Amino acids and the brain: do they play a role in “central fatigue”? Int J Sport Nutr Exerc Metab. 2007;17 Suppl:S37-46; Howatson G, Hoad M, Goodall S, Tallent J, Bell PG, French DN. Exercise-induced muscle damage is reduced in resistance-trained males by branched chain amino acids: a randomized, double-blind, placebo controlled study. J Int Soc Sports Nutr. 2012;9(1):20. doi:10.1186/1550-2783-9-20; Blomstrand E, Eliasson J, Karlsson HKR, Köhnke R. Branched-Chain Amino Acids Activate Key Enzymes in Protein Synthesis after Physical Exercise. J Nutr. 2006;136(1):269S-273S. doi:10.1093/jn/136.1.269S.
Mourier A, Bigard A, Kerviler E de, Roger B, Legrand H, Guezennec C. Combined Effects of Caloric Restriction and Branched-Chain Amino Acid Supplementation on Body Composition and Exercise Performance in Elite Wrestlers. Int J Sports Med. 1997;18(01):47-55. doi:10.1055/s-2007-972594.
Hulmi JJ, Lockwood CM, Stout JR. Effect of protein/essential amino acids and resistance training on skeletal muscle hypertrophy: A case for whey protein. Nutr Metab (Lond). 2010;7(1):51. doi:10.1186/1743-7075-7-51.
Wolfe RR. Branched-chain amino acids and muscle protein synthesis in humans: myth or reality? J Int Soc Sports Nutr. 2017;14(1):30. doi:10.1186/s12970-017-0184-9.
Saudan C, Baume N, Emery C, Strahm E, Saugy M. Short term impact of Tribulus terrestris intake on doping control analysis of endogenous steroids. Forensic Sci Int. 2008;178(1):e7-e10. doi:10.1016/j.forsciint.2008.01.003; Antonio J, Uelmen J, Rodriguez R, Earnest C. The effects of Tribulus terrestris on body composition and exercise performance in resistance-trained males. Int J Sport Nutr Exerc Metab. 2000;10(2):208-215; Rogerson S, Riches CJ, Jennings C, Weatherby RP, Meir RA, Marshall-Gradisnik SM. The Effect of Five Weeks of Tribulus terrestris Supplementation on Muscle Strength and Body Composition During Preseason Training in Elite Rugby League Players. J Strength Cond Res. 2007;21(2):348. doi:10.1519/R-18395.1.
Koehler K, Parr MK, Geyer H, Mester J, Schänzer W. Serum testosterone and urinary excretion of steroid hormone metabolites after administration of a high-dose zinc supplement. Eur J Clin Nutr. 2009;63(1):65-70. doi:10.1038/sj.ejcn.1602899.
Topo E, Soricelli A, D’Aniello A, Ronsini S, D’Aniello G. The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats. Reprod Biol Endocrinol. 2009;7(1):120. doi:10.1186/1477-7827-7-120.
Willoughby DS, Leutholtz B. D-Aspartic acid supplementation combined with 28 days of heavy resistance training has no effect on body composition, muscle strength, and serum hormones associated with the hypothalamo-pituitary-gonadal axis in resistance-trained men. Nutr Res. 2013;33(10):803-810. doi:10.1016/J.NUTRES.2013.07.010; D’Aniello G, Ronsini S, Notari T, et al. D-Aspartate, a Key Element for the Improvement of Sperm Quality. Adv Sex Med. 2012;02(04):45-53. doi:10.4236/asm.2012.24008; Topo E, Soricelli A, D’Aniello A, Ronsini S, D’Aniello G. The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats. Reprod Biol Endocrinol. 2009;7(1):120. doi:10.1186/1477-7827-7-120.
West DWD, Phillips SM. As
sociations of exercise-induced hormone profiles and gains in strength and hypertrophy in a large cohort after weight training. Eur J Appl Physiol. 2012;112(7):2693-2702. doi:10.1007/s00421-011-2246-z.
Ibid.
Hartgens F, Kuipers H. Effects of androgenic-anabolic steroids in athletes. Sports Med. 2004;34(8):513-554.
Powers ME, Yarrow JF, Mccoy SC, Borst SE. Growth Hormone Isoform Responses to GABA Ingestion at Rest and after Exercise. Med Sci Sport Exerc. 2008;40(1):104-110. doi:10.1249/mss.0b013e318158b518.
Conaglen HM, Suttie JM, Conaglen J V. Effect of deer velvet on sexual function in men and their partners: a double-blind, placebo-controlled study. Arch Sex Behav. 2003;32(3):271-278; Syrotuik DG, MacFadyen KL, Harber VJ, Bell GJ. Effect of elk velvet antler supplementation on the hormonal response to acute and chronic exercise in male and female rowers. Int J Sport Nutr Exerc Metab. 2005;15(4):366-385; Sleivert G, Burke V, Palmer C, et al. The effects of deer antler velvet extract or powder supplementation on aerobic power, erythropoiesis, and muscular strength and endurance characteristics. Int J Sport Nutr Exerc Metab. 2003;13(3):251-265.
Katzenschlager R, Evans A, Manson A, et al. Mucuna pruriens in Parkinson’s disease: a double blind clinical and pharmacological study. J Neurol Neurosurg Psychiatry. 2004;75(12):1672-1677. doi:10.1136/jnnp.2003.028761; Shukla KK, Mahdi AA, Ahmad MK, Shankhwar SN, Rajender S, Jaiswar SP. Mucuna pruriens improves male fertility by its action on the hypothalamus–pituitary–gonadal axis. Fertil Steril. 2009;92(6):1934-1940. doi:10.1016/j.fertnstert.2008.09.045.
Branch JD. Effect of creatine supplementation on body composition and performance: a meta-analysis. Int J Sport Nutr Exerc Metab. 2003;13(2):198-226.
Volek JS, Ratamess NA, Rubin MR, et al. The effects of creatine supplementation on muscular performance and body composition responses to short-term resistance training overreaching. Eur J Appl Physiol. 2004;91(5-6):628-637. doi:10.1007/s00421-003-1031-z.
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