and external factors, 211
and ‘fright-fight-flight’, 45, 47
and implanted electrodes, 41
medicolegal history of, 208
and non-REM parasomnias, 176
and open eyes, 66
questions concerning, 52–3
‘quite extreme’, 37
self-harm during, 37
sleep-talking a variation of, see sleep-talking
and sound sleep, 54
and SPEC T, 40–1, 42
and surgery, 41–2
treatments for, drug and non-drug, 56–7
triggered by sounds, 53
and twins, 53
Socrates, 216
sodium oxybate, 136–7, 283
Sophie (Adrian’s daughter), 113–14
suprachiasmatic nucleus, 21–2, 27, 28, 31, 33
swine flu, 127
Tamiflu, 127
TATT (tired all the time), 76–7 (see also Maria)
temporal lobe, 123, 170, 171, 172, 177
thalamus, 244, 251
tired all the time (TATT), 76–7
Tom (sleep problems), 198–201, 203–7, 212–15, 216, 217
rape conviction of, 203–7, 212–13, 215
topiramate, 229
Tourette, Georges Gilles de la, 96
twins, and sleepwalking, 53
untreatable sleepiness, 98–9
Vincent (at Guy’s), 15–17, 22, 24–7, 28, 29, 32, 33–4, 35
and excellent exam grades, 32
visual cortex, 6, 171, 172
von Economo, Constantin, 116, 117
Walker, Matthew, 269, 275–6
Willis, Thomas, 144
World Health Organization, 30
‘Yesterday’, 270
Zeitgebers, 19, 22, 27, 29
First published in Great Britain by Simon & Schuster UK Ltd, 2019
A CBS COMPANY
Copyright © Guy Leschziner, 2019
The right of Guy Leschziner to be identified as the author of this work has been asserted in accordance with the Copyright, Designs and Patents Act, 1988.
1 3 5 7 9 10 8 6 4 2
Simon & Schuster UK Ltd
1st Floor
222 Gray’s Inn Road
London WCIX 8HB
www.simonandschuster.co.uk
www.simonandschuster.com.au
www.simonandschuster.co.in
Simon & Schuster Australia, Sydney
Simon & Schuster India, New Delhi
The author and publishers have made all reasonable efforts to contact copyright-holders for permission, and apologise for any omissions or errors in the form of credits given. Corrections may be made to future printings.
A CIP catalogue record for this book is available from the British Library.
Hardback ISBN: 978-1-4711-7635-7
Trade Paperback ISBN: 978-1-4711-7636-4
eBook ISBN: 978-1-4711-7637-1
Typeset in Perpetua by M Rules
Printed and bound by CPI Group (UK) Ltd, Croydon, CRO 4YY
Simon & Schuster UK Ltd are committed to sourcing paper that is made from wood grown in sustainable forests and support the Forest Stewardship Council, the leading international forest certification organisation. Our books displaying the FSC logo are printed on FSC certified paper.
The Nocturnal Brain Page 33