by Dave Asprey
11.Jane A. Mitchell and David Bishop-Bailey, “PPARβ/δ a Potential Target in Pulmonary Hypertension Blighted by Cancer Risk,” Pulmonary Circulation 9, no. 1 (June–March 2019): 2045894018812053, https://doi.org/10.1177/2045894018812053.
12.Estelle Woldt et al., “Rev-erb-α Modulates Skeletal Muscle Oxidative Capacity by Regulating Mitochondrial Biogenesis and Autophagy,” Nature Medicine 19, no. 8 (August 2013): 1039–48, https://doi.org/10.1038/nm.3213.
13.Jill P. Smith et al., “Low-Dose Naltrexone Therapy Improves Active Crohn’s Disease,” American Journal of Gastroenterology 102, no. 4 (April 2007): 820–28, https://doi.org/10.1111/j.1572-0241.2007.01045.x.
14.Jarred Younger, Luke Parkitny, and David McLain, “The Use of Low-Dose Naltrexone (LDN) as a Novel Anti-Inflammatory Treatment for Chronic Pain,” Clinical Rheumatology 33, no. 4 (2014): 451–59, https://doi.org/10.1007/s10067-014-2517-2.
15.Jarred Younger and Sean Mackey, “Fibromyalgia Symptoms Are Reduced by Low-Dose Naltrexone: A Pilot Study,” Pain Medicine 10, no. 4 (May–June 2009): 663–72, https://doi.org/10.1111/j.1526–4637.2009.00613.x; Jarred Younger et al., “Low-Dose Naltrexone for the Treatment of Fibromyalgia: Findings of a Small, Randomized, Double-Blind, Placebo-Controlled, Counterbalanced, Crossover Trial Assessing Daily Pain Levels,” Arthritis & Rheumatology 65, no. 2 (February 2013): 529–38, https://doi.org/10.1002/art.37734.
16.Renee N. Donahue, Patricia J. McLaughlin, and Ian S. Zagon, “Low-Dose Naltrexone Suppresses Ovarian Cancer and Exhibits Enhanced Inhibition in Combination with Cisplatin,” Experimental Biology and Medicine (Maywood) 236, no. 7 (July 2011): 883–95, https://doi.org/10.1258/ebm.2011.011096.
17.Burton M. Berkson, Daniel M. Rubin, and Arthur J. Berkson, “Reversal of Signs and Symptoms of a B-cell Lymphoma in a Patient Using Only Low-Dose Naltrexone,” Integrative Cancer Therapies 6, no. 3 (September 2007): 293–96, https://doi.org/10.1177/1534735407306358; Ian S. Zagon, Renee N. Donahue, and Patricia J. McLaughlin, “Opioid Growth Factor-Opioid Growth Factor Receptor Axis Is a Physiological Determinant of Cell Proliferation in Diverse Human Cancers,” American Journal of Physiology—Regulatory, Integrative, and Comparative Physiology 297, no. 4 (October 2009): R1154–61, https://doi.org/10.1152/ajpregu.00414.2009.
18.Gordon L. Cheng et al., “Heroin Abuse Accelerates Biological Aging: A Novel Insight from Telomerase and Brain Imaging Interaction,” Translational Psychiatry 3, no. 5 (May 21, 2013): e260, https://doi.org/10.1038/tp.2013.36.
19.Franco Cataldo, “Interaction of C(60) Fullerene with Lipids,” Chemistry and Physics of Lipids 163, no. 6 (June 2010): 524–29, https://doi.org/10.1016/j.chemphyslip.2010.03.004.
20.Yuriy Rud et al., “Using C60 Fullerenes for Photodynamic Inactivation of Mosquito Iridescent Viruses,” Journal of Enzyme Inhibition and Medicinal Chemistry 27, no. 4 (August 2012): 614–17, https://doi.org/10.3109/14756366.2011.601303.
21.Yuliana Pineda Galvan et al., “Fullerenes as Anti-Aging Antioxidants,” Current Aging Science 10, no. 1 (2017): 56–67, https://doi.org/10.2174/1874609809666160921120008.
22.Tarek Baati et al., “The Prolongation of the Lifespan of Rats by Repeated Oral Administration of [60]Fullerene,” Biomaterials 33, no. 19 (2012): 4936–46, https://doi.org/10.1016/j.biomaterials.2012.03.036.
LIST OF SEARCHABLE TERMS
The page numbers in this index relate to the printed version of this book; they do not match the pages of your ebook. You can use your ebook reader’s search tool to find a specific word or passage.
acacia fiber, 195
activated charcoal, 136–38, 143
ActivePQQ, 125
Actos (pioglitazone), 219
ADD (attention deficit disorder), 12–13
Adelson, Harry, 211–15, 217
adenosine triphosphate (ATP), 9, 94, 95, 240
adipose tissue, 52
adsorption, 136
AEP (amino ethanol phosphate), 29, 40
aflatoxin, 137
AGEs (advanced glycation end products), 31–32, 36, 45, 46, 112, 139
agglutinins (WGA), 194–95
aging
overview, 24
autoimmune diseases’ role in, 188
autophagy for slowing down, 19
from birth control pills, 168, 169
and calcification of tissue, 140–41
and deep sleep decrease, 70
and heart rate variability, 72
and heavy metal toxicity, 134
hormone level reduction, 158–59
and leaky gut syndrome, 199
lessons from Greek myths, xvii, 207, 227, 265
and telomere length, 37
See also death by a thousand cuts; Seven Pillars of Aging
aging backward, 204–64
overview, xviii, 96, 101–2, 232–33, 248
NAD+ to NADH ratio, 152–53
and peptides, 248–52
and stem cell therapy, 211
See also multiple methods for strengthening your body
alchemy, xiv
Alitura skin-care products, 230
alpha-lipoic acid (ALA), 135, 143
alpha-melanocyte-stimulating hormone (alpha-MSH), 240
alpha-MSH (alpha-melanocyte-stimulating hormone), 240
aluminum, 130
Alzheimer’s disease
overview, 17–19
and blood sugar level, 14, 113–15
development of, 104–5
effects of nicotine on, 120
and heavy metal toxicity, 34
incidence of, 4
and insulin, 115
and Klotho in cerebrospinal fluid, 228
light therapy for, 111
prevention, 65, 104–5, 114–15, 128
Amen, Daniel, 17–18
American Academy of Anti-Aging Medicine conference, 169
American Cancer Society, 66–67
amino acids
overview, 47–48, 248
EDTA, 139–41
GHK-Cu, 229–30, 231, 249
glycine, 43, 234–36
L-theanine, 125, 128
L-tyrosine, 171–72
peptides, 248–52, 263
vitamin C, collagen, and, 7
amino ethanol phosphate (AEP), 29, 40
amyloid proteins
overview, 33–34
curcumin vs., 126
glymphatic system vs., 65
and heavy metals, 34–35
and high sugar diet, 112–13
light therapy for breaking up, 111
and microglial cells, 108
monitoring, 126
NAD+ for avoiding buildup, 152
vitamin D vs., 87
anaerobic metabolism, 19
andropause, 159
aniracetam, 118
antibacterial, coconut oil as, 182
antibiotics
in animals grown for human food, 12, 47, 48, 201
and antibiotic-resistant bacteria, 12, 146, 201–2
Asprey’s use of, in childhood, 3, 185, 201–2
and gray hair, 243
and microbiomes, 185, 187–88, 190
ozone therapy vs., 144, 146, 147–48
anti-inflammatories
alpha-MSH hormone, 240
butyric acid, 51–52
coconut oil, 182
omega-3 fats, 53
short-chain fatty acids, 11–12
antioxidants
anti-aging properties, 9
carbon 60, 261
for catalase production increase, 241
curcumin, 80, 126–27, 219
dismutase, 127
fisetin, 30
for heavy metal detox, 134–36
lion’s mane mushroom, 125–26
and metabolites from fasting, 49
methylene blue, 238–39
polyphenols, 30, 40, 59, 197, 201, 203, 246
PQQ, 124–25
superoxide dismutase, 122–23
vitamin C, 236
See also glutathione
antioxidant therapy via IV, 22
anxiety disorders. See stress
apoptosis, 9, 19, 25, 37, 38–39
Apple’s Night Shift (warm screen colors), 81–82
arsenic, 35, 130–33, 138, 141
arthritis
prevention, 234
and senescent cells, 29
from senescent cells, 29
from toxic mold exposure, 3
treatments, 155, 181, 211, 216–17, 218–19
ashitaba (Japanese herb), 30
ashwagandha, 241
Asperger’s syndrome, 12–13
Asprey, Anna, 147–48
Asprey, Dave
allergy tests reveal mold allergy, 7
business school, 17–18, 55, 68, 103
childhood, xix, 3–4
college years, 4, 15–16, 17
and Epitalon, 38
hacking his brain’s language processing area with a laser (not recommended), 110–11
Hashimoto’s thyroiditis, 5–6
home laboratory
hormone levels, 5–6, 156
light therapy for whiplash, 91–92
living proclamation, 265–66
meeting his future wife, 169–70
parasite introduction into his gut, 187
POTS from toxic mold exposure, 12–13
questioning conventional wisdom about diet, 14–15
studying anti-aging results, 6
Tibet and Nepal trip, 55–57
on trying new methods, 207–8
Viome microbiome analysis results, 201–2
“zero carbs for nineteen days” experiment, 69
Asprey, Lana
infertility diagnosis and cure, 169–70
stem cell treatments, 213–14, 220
treating Anna’s scratched ear, 147–48
utilizing red light panels, 93
asthma, 177
astragalus (herb), 39
atherosclerosis, 10–11, 172
athletes and performance-enhancing substances, 253–54
Atmospheric Cell Trainer, 212–13
ATP. See adenosine triphosphate
attention deficit disorder (ADD), 12–13
autoimmune diseases
and amyloids, 33–34
Hashimoto’s thyroiditis, 5–6
and leaky gut syndrome, 198
on modafinil, 118–21
and Naltrexone, 259, 263
prevention, 187–88
and wheat, 42
autonomic nervous system, 71–72
autophagy, 19, 34, 48–49
autophagy stimulation, 22
Ayurvedic medicine, 30, 39, 136, 181–82, 238, 241
bacteria
overview, 185–86
in breast milk, 189
and histamines, 192
human acquisition of, 7
interaction with other bacteria, 11–12
mold as lethal threat to, 7–8
reducing mouth bacteria, 182
See also gut bacteria
bakuchiol, 238
baldness, 242–45
Basis, 68
BDNF (brain-derived neurotrophic factor), 117, 125–26
benzophenones, 244, 245, 246
betaine hydrochloride (HCL), 235
Better Baby Book, The (Asprey and Asprey), 170
bifidobacteria, 198
Big Food companies and glyphosate, 44
biohackers, xiv, 213
biohacking
overview, xvii–xviii, 22
Asprey’s home laboratory, 93, 107, 146–48
and hormones, 170–72
with rapamycin, 30
rule 1: remove what makes you weak, 10
See also multiple methods for strengthening your body
bioidentical hormone replacement therapy
Asprey’s experience with, 6, 156
DHEA’s longevity-enhancing effects, 162–63, 173
human growth hormone, 165–66
medical tests prior to, 160–61, 163
oxytocin, 163–65
pellets put under skin by a doctor, 162
as smart drug, 159
synthetic hormones vs., 160
testosterone, 161–62, 257
for thyroid hormone, 172
traditional view of, 157–58, 159–60
Wiley’s research and recommendations, 157, 159
bioregulator peptides, 249–50, 263
birth control pills, 168, 169
bite alignment, 178–80
bite guards, 178–79, 180–81, 184
blackout curtains, 80–81
black pepper extract, 126–27
blood-brain barrier and toxic metals, 130
blood flow and leaky gut syndrome, 198
blood flow and trigeminal nerve, 180
blood pressure and Klotho levels, 228
blood sugar
and AGEs, 31–32, 45, 112
and bad quality sleep, 66
damage caused by, 13–14, 31–32, 112–13
fasting blood sugar test, 5
and glucosamine, 15
monitoring, 113–14
and Ostarine, 256
stabilizing your level of, 128
and sugar cravings, 44–45
and UVB exposure, 87
blue (junk) light, 78–82, 83, 85–90, 97
bones, keeping calcium in, 140
boron supplements, 219, 231
Boston University, 43, 111–12
BPC157 healing peptide, 252
brain
blood-brain barrier and toxic metals, 130
blood flow and trigeminal nerve, 180
gut-brain axis, 199–200
prefrontal cortex, 119
rejuvenating with GHK, 229
reticular activating system and trigeminal nerve, 178–79
thallium damage, 131
brain-derived neurotrophic factor (BDNF), 117, 125–26
brain health and processes, 103–28
overview, 103–4
hacking the language processing area with a laser (not recommended), 110–11
hippocampal atrophy, 25–26, 107
microglial cells, 17, 111, 115, 194
and monounsaturated fats, 52–53
neurofeedback, 105–9, 128
red/infrared laser therapy for, 109–12
and sleep, 64, 69–70
See also cognitive dysfunction; neurotransmitters
brain herbs, supplements, and drugs
overview, 116–17
Brain Octane Oil, 57–58, 115, 154, 201
coenzyme Q10/idebenone, 123–24
curcumin, 126–27
He Shou Wu, 127
lion’s mane mushroom, 125–26
L-theanine, 125
microdose deprenyl/selegiline, 122–23
microdose nicotine, 120–21
modafinil, 118–20
piracetams, 117–18
pyrroloquinoline quinone, 124–25
Bredesen, Dale, 104
Brigham and Women’s Hospital, Boston, 11
Bulletproof Coffee, 57, 59, 60, 90, 115, 139, 192–93, 201, 246
Bulletproof Diet, The (Asprey), 194
Bulletproof Diet and sleep needs, 67
Bulletproof Radio, xvi–xvii, xviii, 60
butter from grass-fed cows, 53, 55, 57
butylparaben, 168
butyric acid, 198
C360 Health, 261–62
cadmium, 34, 35, 130–33, 136, 141
calcification of tissue, 140–41
calcium, 140
calorie restriction, 154, 219
Campbell, T. Colin, 45, 46–47
Campbell, Thomas M., II, 45, 46–47
cancer
contributing factors, 5
and genetics, 18–19
incidence of, 4, 18
and middle-age hormone level reduction, 158–59
modified citrus pectin vs., 138–39
modified NK cells vs., 223–25
and Naltrexone, 259
from outdoor blue light, 79
tumors overexpress substance P, 177
Candida fungus, 190–91, 192, 201
capsaicin for dental health, 181
carbohydrates
effect of decreasing intake of, 16
hormone depletion caused by, 166
pairing with blood sugar reducing supplements or fiber, 113, 128
“zero carbs for nineteen days” experiment, 69
carbon 60 and Carbon60 Plus, 260–62, 263
cardiolipin, 237
cardiovascular disease, 12–13, 22, 131. See also heart disease; vascular system
carotenoid supplements, 82
cartilage growth with ozone therapy, 150
catalase, 241
cavemen and fire, xiii–xiv, 207, 208
cayenne pepper for dental health, 181
CDC (Centers for Disease Control and Prevention), 4
celiac disease, 42, 198
Cell Host & Microbe (journal), 198
cell membranes, 51, 52
cellular apoptosis, 9, 19, 25, 37, 38–39
Centers for Disease Control and Prevention (CDC), 4
CFL (compact fluorescent light) bulbs, 78, 81, 132
chelation therapy and chelating agents
overview, 34–35, 143
EDTA, 139–41
glutathione, 134–35
children and dogs, playing with, 165
China, xxi, 131
China Study, The (Campbell and Campbell), 45, 46–47
chlorella, 138, 143
cholesterol
and activated charcoal, 137
and low thyroid hormones, 172
testosterone made from, 166
chondroitin sulfate, 217
chromium, 130
chromium picolinate, 113
circadian clock disruptions, 79, 88, 108
circadian rhythm
overview, 84–85, 88
and blue light, 78–79
effect of food, light, and too little sleep, 64
and ketones, 60, 61
and red light, 89–90, 93
and vitamin D, 87
CLA (conjugated linoleic acid), 53
Clomid, 257
Clostridium difficile bacteria, 189
coconut oil, 57–58, 182
coenzyme Q10/idebenone, 123–24
cognitive dysfunction
overview, 104–5
Asprey’s diagnosis of, 17–18
brain shrinkage, 25–26
and jaw misalignment, 180
laser therapy vs., 109–12
LED lights flickering vs., 111
from toxic mold exposure, 5
vascular issues and, 12–13
See also brain health and processes
cognitive enhancement, 30, 115, 120–21, 128. See also brain herbs, supplements, and drugs
collagen
overview, 233–36