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The Complete Adversary Cycle: The Keep, the Tomb, the Touch, Reborn, Reprisal, Nightworld (Adversary Cycle/Repairman Jack)

Page 134

by F. Paul Wilson


  So to give you an example, let's take Attila the Hun and mate him with Joan of Arc. We could get a strong, brave, ferocious, idealistic supersoldier. Or we could get a 98-pound anemic accountant. Attila and Joan, no matter how strong and brave and aggressive they each may be, have recessive anemic accountant genes hiding on their chromosomes. If we take from each a haploid gamete rich in recessive anemic accountant genes and pair them, we will get an anemic accountant. The pairing of any two random gametes from each could result in anything between the two extremes. The odds can be skewed in your favor by rigorous investigations of the family trees, but it's still a crapshoot. And since humans don't breed like mice or rabbits, it would take lots of luck and many generations to breed a supersoldier army.

  What was needed was a way to move a desirable genotype intact (the word intact cannot be overemphasized here) from generation to generation. In other words, we had to find a way of creating identical twins (or triplets or quints, or what have you) a generation removed from the original.

  We needed to produce a series of beings genetically identical to their parent. (Note the singular, please.)

  Clones, if you will.

  We had to learn how to clone a human being.

  Now, when you remove yourself from the fray and sit back and consider it without emotion, that is a pretty frightening concept. But Derr and I were in the thick of the fray. We were filled with the passion and fervor of discovery. Nothing frightened us. Questions of ethics or responsibility were far from our minds.

  The only question that mattered was: How?

  A tissue culture was out. A human body is a complex system of many different tissues. We could not culture out individual organs and patch them together like a modern Frankenstein. What we needed was a way to induce a human ovary to form an egg with a nucleus that was diploid instead of haploid. The result would be cloning by parthenogenesis, and only females would result, but it would be a start.

  Then a chance remark by Derr set us on the right track. He said, "Too bad we can't just get hold of some ova and plop the genotype we want into them."

  It was one of those rare moments of shared epiphany. You look at each other with wide eyes, then leap up and jump around and begin shouting ideas back and forth like a couple of madmen. That was Derr and I.

  Looking back now, I think that perhaps we truly were mad.

  But it was a glorious madness. I can't describe the excitement we felt. And even now I wouldn't trade those times for anything. We shared a feeling of masterfulness. I'm not sure there is such a word, but if it doesn't exist, it should. We felt that we were on the verge of something epochal, that just beyond our questing fingertips lay the secret of mastering Creation.

  And it was just the two of us. That was the most enthralling part of it. Only Derr and I had the Big Picture. We had technicians for the scut work, of course, but the duties of each were narrowly circumscribed. My three-floor town house was partially converted into two labs. Some worked in the third-floor lab, others worked in the basement lab. Only we knew where the sum of all the scut work was headed. The whole would truly be greater than the sum of its parts.

  We started small. We looked for an aquatic, oviparous reptile with good-size eggs. We settled for an amphibian. That was Derr's idea. He had trained in Europe where frogs are frequently used for research. We obtained a supply of green frogs and some special pure-white albino frogs. We were ready to begin.

  After much trial and error we perfected a microscopic technique of removing the haploid nucleus from the egg of a green frog and replacing it with a diploid nucleus removed from a body cell of a white frog. All the genetic information from the albino frog now resided in the egg cell from the green. The egg cell, in a sense, had been fertilized. After many failures and botch-ups, we eventually got it right. Soon we were awash in white tadpoles.

  This was ground-breaking work that would have set the scientific community (and no doubt the religious and philosophical communities as well) on its ear. Think of it: We were reproducing without recourse to the sexual process! This was a mammoth achievement!

  But we could not publish. Everything we were doing in Project Genesis was classified top secret. In a very real sense the government owned our work. I won't say it made no difference to us. It most certainly did. But we felt we could wait. We could not publish now, but someday we would. At that moment we were, quite frankly, much too busy even to consider wasting the time it would take to document our work for publication.

  After perfecting our microtechnique we moved on to mammals. I won't bore you with the details of each species we tried—it's all recounted on a day-by-day basis in the gray journals—but suffice it to say that after a seemingly endless run of daily grinding work, we felt we were ready to tackle the human ovum.

  Our first problem, naturally, was where to get the raw material. One does not simply send out to a laboratory supply house and order a gross of human ova. We were entering a very sensitive area. We would have had to tread softly even if we were on our own, but with the extra burden of security from the government, we felt hamstrung.

  I then came up with the bright idea of letting the government help us out. I told our contact in the War Department that we needed human ovaries. Colonel Laughlin was one of the few in the entire government who knew of the existence of Project Genesis. He paused only a moment, then said, "How many?"

  It wasn't long before we began receiving regular shipments of human ovaries in iced saline solution. Some were cancerous, but many were merely cystic and provided us with a small supply of viable normal ova. These we nurtured in a nutrient solution while we practiced our microtechniques.

  We came to learn that the human ovum would not tolerate too much manipulation. The double trauma of removing the original nucleus and inserting another was apparently more than the cell membrane could stand. We ruptured one test ovum after another. So we devised a method of using ultraviolet light to inactivate the original genetic material within the ovum. We could then leave the old haploid nucleus where it was and insert the new nucleus right next to it in the cytoplasm.

  Finally it came time to find the human diploid nuclei to transplant into the ova. This was going to be a problem. Along the way, as Derr and I progressed through a number of mammals toward human tissue, we had learned that we could not use just any nucleus from any cell in a mammal's body. Once a mammalian cell becomes fully differentiated (i.e., becomes a functioning part of the skin or the liver or any other organ), its nucleus loses its capacity to regenerate an entire organism. We had to go to the wellspring of the gamete, the diploid cell that divides into two haploid gametes: the primary spermatocyte. And to obtain those we would have to burrow into a healthy, functioning human testicle.

  I volunteered myself.

  Call it part of the madness that was upon us. Call it pragmatism as well. Colonel Laughlin sent us what testicular specimens he could, but none of them were suitable. Undamaged, undiseased testicles were difficult to come by.

  Besides, I had a number of reasons for wanting my own genotype thrust into the ovum. The first might be called ego. I admit that without apology. This whole project was my idea. I wanted to see my work result in a new generation of Roderick Hanleys. The second was more practical: I had to be certain of the race of the donor genotype. Do not rear up on your egalitarian steed at this, I had my reasons, and soon you will understand them.

  Through Colonel Laughlin we arranged for an army urologist to do a wedge resection on my left testicle under local anesthesia. (He tied off an annoying varicocele while he was there, so it was not a totally frivolous procedure from the surgeon's viewpoint.) Derr took the section and culled out the primary spermatocytes. With these living and thriving in their nutrient bath, we were ready to begin the next phase.

  It was time to find an incubator—a woman who would host the manipulated ovum and bear the resultant child.

  Derr and I had decided on a number of characteristics: She had to be young, healthy
, and single, with a clockwork menstrual cycle. And she had to be Negro. As I alluded above, this final criterion was not prompted by a racist bias. It was based on solid, scientific reasoning. Our plan was to insert a diploid nucleus from one of my primary spermatocytes into a human ovum and, in turn, insert that ovum into the uterus of a human female. We had to be sure that the resultant child (if all went as hoped) had actually arisen from the manipulated cell.

  My genotype is lily white. My parents came from the British Isles late in the last century and I doubt very much that anyone in my family tree had ever even seen a Negro, much less had sexual relations with one. Therefore, if after nine months our host mother gave birth to a male who exhibited the slightest hint of Negroid features, we could be quite sure that the child did not carry my genotype. (A female child would obviously not be ours, either.)

  Although not exactly parallel, we were doing on human terms what we had done with the frogs when we started: inserting the genotype from an albino into an egg from a green frog. Just as a white hatchling was proof of our success with the frogs, a lily-white infant boy from a Negro womb would confirm our success with a human genotype. (Yes, I'm sure you can come up with a very rare exception, but we had to be satisfied with this level of control.)

  Once we had proven we could do it, we would report our success to the government. The War Department could then begin its search for the man who would provide the genotype for the American supersoldier.

  Finding the woman: That was left to me. And with good reason. Once Project Genesis started, I lived a virtually celibate life. There was no room in my life for sex, only the project, the project! Ah, but before that I was quite the ladies' man, the bon vivant, the Man About Town. I had many friends, high and low, who knew that no matter where or when they threw a party, Rod Hanley could be counted on to appear. I was known in the poshest night spots and the sleaziest dives. And I knew men who could supply women who would do just about anything for a price.

  That is how we began our relationship with the amazing Jasmine Cordeau. I don't have any photographs of her, but if you could see her, you'd know what I mean. She was a stunning Negress. Her skin was as black as the night, and her figure was something every red-blooded male dreams of. Fresh from the bayous outside New Orleans, she migrated to New York and became a popular ecdysiast—stripteaser seems much too common a term for what she did on the stages of the uptown after-hours clubs I once frequented. But as the Great Depression steadily deepened despite two terms of grandiose promises from FDR, she had to turn to prostitution to make ends meet.

  For a while, Derr and I gave her a respite from that.

  I knew her "manager," who was acting as her procurer at the time. After a gynecological exam certified her free from venereal disease, I persuaded him to let us take and keep her for up to two years. He would be paid one thousand dollars per month for that period, no questions asked. He eagerly agreed. (If $12,000 a year seems like a princely sum now, please realize that it was worth much much more at the start of 1941.)

  All we had to do was convince Jazzy, as she called herself. We met with her and explained what we wanted: She was to allow herself to become impregnated by us and to bear the resultant fetus to term. During the period in question she was to live with us in comfort and class, but under no circumstances could she leave my town house unless accompanied by either Derr or myself.

  Jazzy was understandably reluctant at first. She was used to the fast life and, for obvious reasons, did not want to be pregnant. She was a stripper by profession and her body was her meal ticket. She was rightfully protective of it; she didn't want to get fat, and she didn't want stretch marks.

  She didn't want to be a prostitute, either, but with the Depression hanging on as it was, she had no alternative. "A gal's gotta eat," she would say. We promised her she'd eat very well, that we would help her take good care of her body during the pregnancy, and that if she bore us the baby we planned, she would receive a bonus of $10,000.

  She agreed.

  We sent the technicians packing with a month's pay so that we would have the town house to ourselves.

  We were ready to begin.

  The procedure was relatively straightforward and simple. Derr and I would "fertilize" an inactivated ovum (see above) by extracting a diploid nucleus from one of my primary spermatocytes and inserting it into the ovum. When we had three successful transfers, we would save them until Jazzy entered the ovulatory phase of her menstrual cycle. Then she would get on the examining table and assume the lithotomy position. We would then insert a fine rubber tube through the os of her cervix and inject a solution containing the three "fertilized" ova into her uterus.

  After that it was out of our hands. All we could do was hope that the one of the ova would find its way to the endometrium—the lining of the uterus—and attach itself. There was, of course, the theoretical threat of all three ova implanting and Jazzy bearing triplets, but neither Derr nor I was concerned about that. We knew we would be extremely lucky if just one implanted.

  We first inseminated her in mid-December 1940. She menstruated on New Year's Day. We tried again in mid-January, but her period arrived right on schedule at the end of the month. And so it went, through the winter and into the spring. Each month we would hold our collective breaths as her period came due, and each month we would be disappointed by the cramps and menstrual flow.

  She was due for a period in late April. By May 1st, she was late. I stopped believing in God when I was 8, but I remember saying silent prayers during that time. May 2nd and 3rd, still no show. Around midnight on May 3rd, however, she gave us a bad scare. She had been feeling tired and so she had gone to bed early. Suddenly the town house was shaken by her shrill, horrified screaming. We ran to her, and when we found her doubled up in her bed, clutching her. abdomen, we feared the worst—a miscarriage. But physically she was fine. The commotion proved to be the result of a particularly frightening nightmare. It must have been a lollapalooza because the poor thing's tremors were shaking the whole bed. It took us a long while, but finally we quieted her down and got her off to sleep again.

  Four days late became a week late became two weeks late. Jazzy complained of breast tenderness and morning sickness. A pregnancy test was positive. Jazzy had not been out of the house for a minute, and neither of us had had sexual relations with her.

  We had done it!

  What a celebration we had! Champagne, caviar, and the three of us dancing to the radio like fools. Derr and I were acting like it was New Year's Eve because, in a way, we knew it was an eve of sorts—the eve of a new epoch for mankind. We were taking the first step toward eliminating the random factors from reproduction, toward allowing humanity a say in Creation, toward remaking humanity in our own design, in our own image.

  I won't say we felt like gods, Jim, but we sure as hell felt like godlings.

  The months crawled by. Jazzy grew restive, moody, became prone to temper tantrums and maniacal outbursts. We noticed personality changes. She didn't like being pregnant, and hated what was happening to her body. She threatened countless times to sneak out and have an abortion, so we kept a close watch on her; we pampered and cajoled her, telling her to hang on, that it was only until January, and after that she'd have a fat wad of money and would be free to go wherever she wanted.

  I remember how, on certain nights when Jazzy was calm and would permit us, Derr and I would kneel at the sides of her bed as she lay there with her swelling abdomen exposed, and we would take turns with the fetalscope (which is like a regular stethoscope except that the cup is attached to a metal band that goes around the examiner's head, allowing him to listen via bone conduction as well as through the conventional earpieces), pressing it against her abdomen to count the faint, rapid beats of the tiny heart within.

  And we would place our hands over her silky skin and feel the kicks and turns beneath it and laugh with wonder.

  She had about a month to go when the Japs hit Pearl Harbor. It wasn't long
afterward that we heard from Colonel Laughlin. He said that with the United States now officially at war with the Axis, strict priorities were being set for the allocation of all research funds. He informed us that if Project Genesis was to "remain viable" (he was so pleased with his little play on words) we would have to come up with something more than albino frogs; we would have to show real progress toward a supersoldier, or at least demonstrate something of military value.

  (I learned later that almost all the available research money was being funneled into the Manhattan Project, and that Genesis never had a chance, anyway. Just as well.)

  Without going into detail (I had learned through the years never to promise more than you are sure you can deliver; promise less, then deliver the knockout!), I told him that a major experiment was coming to fruition and that we should have the results in four to six weeks. He said that was stretching the time limit, but that he could keep the project open until the middle of January but no longer.

  That was fine with us. Jazzy was due around the first of the year.

  You can't imagine our excitement, the agony of the suspense as her due date approached. We were sure we were going to be successful. Even if the child were stillborn, as long as it was male and lily white, we would consider the experiment a complete success. And what outcome could there be other than complete success? We had implanted the altered diploid ovum ourselves, she had had no opportunity to become pregnant by any other means, the viable fetus inside her uterus could be nothing other than my clone, and yet…

  And yet we still had our doubts. No one had ever done this before, or even attempted to do it. The idea that we might be the first in history to take such a momentous step was mind-numbing. We were looking immortality in the eye. Our names would be known the world over. Every history book written from this day forward would include our names, because what we were doing would shape history from this point on.

 

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