by Lucy Inglis
   prosecution of darknet retailers 370
   Reagan’s campaign against drugs 346–7
   relations with China 201
   rise of morphinism 209–14, 221, 251
   spirit addiction 151–3
   use of opium by doctors 204–5
   War on Drugs 338, 339
   war with Spain (1898) 145
   American Board of Commissioners for Foreign Missions 201
   American Civil War (1861–5) 214–19
   American Field Service 277
   American War of Independence 150–1
   American–Philippine War 250–2
   Amin, Hafizullah 312, 313
   Amoy (Xiamen), capture of (1683) 96
   amphetamines 284, 285
   anaesthesia
   early methods 63–4
   and First World War 280
   opium and early use of in 63–6
   anal fistula 65
   Anatolia 116
   Anel, Dominique 210
   Anel syringe 210
   Anglo–Dutch War 88
   Anglo-Oriental Society for the Suppression of the Opium Trade 235–6
   Annan, Kofi 320
   Anslinger, Harry 262
   Anstie, Francis 230
   Antioch, Siege of (1098) 48
   antiseptics
   and First World War 280
   Antwerp 76
   Anzio Effect 286
   Apel, Otto 292, 293
   apomorphine 234, 334, 335–6, 340
   apothecaries 48, 62, 67
   competition between doctors and 130–1
   as valued members of the community 130
   apothecary shops 131–2
   Arab world
   and cannabis 59
   medicine 39–44
   surgical procedures 40–1
   use of opium for medicinal purposes and as an anaesthetic 40, 41, 42–3
   Arcot, Siege of (1751) 169–70
   Arderne, John of 64–6
   Fistula in ano 65
   Arghandab Dam (Afghanistan) 310
   Aristotle 19
   On Sleeping 18
   Arnold, John 132
   ARPANET 368
   Arrow (ship) 196–7
   aspirin 240, 241, 243
   Assizes of Jerusalem 49–50
   Assyrian Herbal, The 10
   Atatürk (Mustafa Kemal) 262
   Atkinson, Leslie ‘Ike’ 298
   Auckland, Lord 303, 304
   Aurelius, Emperor Marcus 23, 24
   Meditations 24
   Auschwitz camp 288
   Avesta 34
   Avicenna (Ibn-Sīnā) 41–4, 47, 53
   The Book of Healing 41–2
   Canon of Medicine 42–3
   Awsiter, John 147
   Ayer, James Cook 207–9
   Ayer’s Almanac 208
   Ayer’s Cherry Pectoral 207–8
   Ayyubid dynasty 49
   Babur 115, 118
   Bacon, Francis 130
   History of Life and Death 123
   The New Instrument of Science 123
   Bactrian camel 28–9
   Badakshan 60
   Baghdad 38, 41
   Banda Islands 86, 87–8
   Banks, Joseph 167
   bankshalls 106–7
   barbiturates 333
   Barboas, Gonçalo Gil 77
   Barker, Fordyce 212
   Barnes, Nicky 298
   Bartholow, Robert 212, 213
   Bayer 240–1, 243
   Bayer Leverkusen 288
   Bayt al-Hikma (House of Wisdom) 38–9
   Beard, George Miller
   American Nervousness 229
   Beat Generation 333–4, 341
   Beddoes, Thomas
   Hygëia 154–5
   Bedford, Duchess of 167
   Beecher, Henry 286
   Begim, Gulbadan 119
   Belon, Pierre 116
   Benevolent Assimilation (1898) 250–1
   Benezet, Anthony
   The Mighty Destroyer Displayed 152
   Bengal 173
   Benzedrine 284, 285
   Bes (Egyptian god) 14
   betel-chewing 93
   Betts, Dr Thaddeus 204
   Betts, Leah 363
   Bhumibol, King 348
   bin Laden, Osama 313, 315, 322
   binomial nomenclature 145
   bitcoin 370
   Black Death (1346–53) 61
   Black Hole incident (1756) 170
   Black Panthers 298
   blacks
   association with cocaine in America 254–5
   Boadicea, Queen 46
   Boko Haram 326
   Bolivia 82
   Bonfadini Report (1876) 270
   Borgognoni, Theodoric 52–3
   Cyrugia 52–3, 54
   Boston Tea Party (1773) 166
   Bowie, David 336, 337, 341, 342
   Boyle, Robert 124, 125
   Brent, Charles 252, 253
   Brezhnev, Leonid 311–12, 313
   Bridgman, E. C. 200–1
   Britain
   and Afghanistan 303–4, 304–5, 307, 321–2
   arrival of Christianity in 45
   attempts at regulating medical profession 228
   and Dangerous Drugs Act (1920) 255
   Dark Ages 45–6
   early evidence of opium poppy in 8–9
   early sea explorations 84–5
   early use of opium in medicines 125–7
   and First Opium War 188–90
   Gin Craze 135–40, 141–2, 145, 363
   heroin addiction 365–6
   and India 112, 115, 163, 170
   Industrial Revolution 181
   and medicine 123–5
   opium smugglers 172–9
   and opium trade 164, 172–9, 182–3
   opium trade with China 164, 178, 182–3
   and Second Opium War 196–9
   tea consumption and demand 91–2, 164–5, 167
   tea trade 165–7
   tobacco habit 95
   trade with Canton 180–1, 185
   trade with China 99–103, 106, 110–12, 176
   trade deals with Spain 88
   trade in the East 87
   trade with Mughal Empire 120–2
   trade with Philippines 247
   Bronze Age 9–15
   Brown, Dr John 149, 154
   Brunonian System of health 149
   Burma 291, 295–6
   Burroughs, William 228, 241–2, 333–7
   Naked Lunch 334–5
   Burton, Robert 143
   The Anatomy of Melancholy 143–4
   Byzantium 25, 33–4, 50–1 see also Constantinople
   Calamity Jane (Martha Jane Burke) 225, 227
   Calkins, Dr Alonzo 228–9, 230
   Camp Bastion (Afghanistan) 324–5
   Campbell, William 305–6
   Can Tintorer (Gavà) 5–6
   cannabis 26, 59, 62, 322, 363, 369
   Canton 102–3, 106–11, 174, 180–5
   attempt by Lin Zexu to end opium trade in 186–9
   and EIC 109–11
   guild system 107–8
   Jardine Matheson and trade in 180–2
   opium missionaries 199–201
   opium trade 179–82, 184, 186–7, 200, 202
   relationship between hongs and merchants 183–4
   removal of EIC’s control over trade 181–2
   taken by British/French forces (1857) 197
   trade with Britain 180–1, 185
   Triads in 183
   Caputo, Philip 299–300
   Carbone, Paul Bonnaventure 267, 268
   carfentanil 374
   Carrhae, Battle of (53BC) 30, 31
   Catalan Atlas 72
   Centers of Disease Control and Prevention (CDC) 373
   Central Intelligence Agency see CIA
   Ceres 16
   Chapman, Nathaniel 203–4
   Chardin, Jean 117
   Charlemagne, King 46
   Chauliac, Guy de 63
   Ch’en Ts’Ang Ch’i 38
   China 2
6–27, 27–29, 38, 80–81
   arrival of Jesuits in (1582) 83
   banning of opium 98, 174, 179
   currency crisis in sixteenth century 80–1
   early sea exploration 73
   European private expeditions to 81
   first appearance of opium in writings of 38
   first English trade voyage to (1637) 99–103
   and First Opium War 188–90, 193–4, 200
   guild system 107–8
   Han dynasty 28–29
   and Hong Kong 103–106
   legalization of opium trade 198, 202
   Ming dynasty 71, 82–3, 94
   movement of Arab Muslims to 38
   opium consumption and addiction 94–5, 96–7, 111–12, 174, 178–9, 186, 202
   opium dens 97
   opium missionaries 199–202
   opium smoking 109
   opium trade 198–9
   opium trade with Britain 164, 178, 182–3
   population 81, 84, 108–9
   Qing dynasty 94, 98, 104, 197–8
   and Second Opium War 196–9
   and Silk Roads 28–9
   Taiping Rebellion 198
   tea trade with Britain 166–7
   tea/tea-drinking 88–9, 90
   tobacco/tobacco smoking 93–4
   trade with Britain 99–103, 106, 110–12, 176
   trade with Philippines 246
   China White 373
   Chinese
   anti-Chinese sentiment in America 222–4, 228
   emigration to America 219–24
   in Hong Kong 194, 352–3
   in Philippines 246, 247–9, 251
   Chinese hongs 108, 183–4
   Chinese Repository 200
   chloroform 280
   Christianity 25, 45–6
   Churchill, Winston 283
   CIA (Central Intelligence Agency) 268–9, 291, 297, 356
   clippers 180–1
   Clive of India (Robert Clive) 163, 168–72
   Clostridium novyi 363
   Cobain, Kurt 342
   Cobden, Richard 197
   Coca-Cola 218
   cocaine 326
   association of American blacks with 254–5
   Cocteau, Jean 330–1, 332, 333
   coffee 90, 91, 92
   Cogotai (envoy) 56
   Cohong 110, 111
   coinage 34
   appearance of opium poppy on 20
   Coleridge, Samuel Taylor 155, 156–7, 159–60
   ‘Kubla Khan’ 156
   Columbus, Christopher 74–5, 80
   Combined Maritime Forces (CMF) 327, 328
   Commutation Act (1784) 166
   compradors 101–2, 107, 108, 110, 111
   Constantine, Emperor 25, 33–4
   Constantinople 25, 33–4, 55
   conquest of by Ottomans (1453) 74
   see also Byzantium
   Convention Against Illicit Trafficking in Narcotic Drugs (1988) 367
   Coptic Christians 44–5
   Coram, Thomas 140
   Corsican Mafia 267–9, 273, 291
   Cosa Nostra 269–75
   Cowper, William 168
   Crete 11
   Crothers, Thomas D. 217, 244
   Crumpe, Samuel 149–50
   An Inquiry into the Nature and Properties of Opium 149–50
   Crusades 46–51, 61, 115
   Cuba
   war of independence from Spain 244–5
   Cueva de los Murciélagos (Granada, Spain) 9
   Cushing, Harvey 277, 278, 281
   Cyprus 13–14
   cyrugicus 47
   da Gama, Vasco 75–6, 78
   Dachau, liberation of (1945) 287–8
   Dai Fou 219–24
   Dalrymple Home for Inebriates 238
   Damiani Report (1881–6) 270, 271
   Dangerous Drugs Act (1920) 255
   Daoud, Mohammad 310, 311–12
   Dark Ages 44–5
   darknet 369–70
   Davenant, Charles 138
   Day, Horace B.
   The Opium Habit 218
   De Quincey, Thomas 155, 157–9, 160, 230, 332
   Confessions of an English Opium-Eater 158, 229
   DEA (Drug Enforcement Agency) (US) 287, 352, 360
   Deadwood (South Dakota) 225–8
   Deadwood (TV series) 224
   Defoe, Daniel 137
   Defour, Judith 139–40
   Deir-el-Medina (Egypt) 14–15
   Demeter (Greek goddess) 16
   Dent, John Yerbury 335
   Dent, Lancelot 185, 187, 201
   Derosne, Charles 161
   Dewey, Thomas E. 273
   dhows 71–2
   diacetylmorphine 233–5, 239–40, 241–2
   see also heroin
   diamorphine 241, 242–3, 255, 285
   Dias, Bartolomeu 74
   Dio, Cassius 30
   Dioscorides, Pedanius 21, 40
   De materia medica 21–2
   diryaq 49
   disease theory 152
   dissection 66, 68
   doctors
   increase in demand for during the plague 63
   and morphine addiction 230
   relationship with apothecaries 130–1, 132
   dolantin 285
   Dost Mohammed Khan 303, 304
   Dover, Thomas 129–30, 132–5
   The Ancient Physician’s Legacy to his Country 133–5
   Dover’s Powder 134–5
   Dreser, Heinrich 240, 241–2
   Drug Enforcement Agency see
   DEA Drunkards Act (1879) 237, 238, 239
   Du Yuesheng 265–7, 352
   Durand Line 306, 307, 311, 321
   dwale 64
   Dylan, Bob 341
   East India Company see EIC
   East Indies
   European exploration of 74–6
   opium use 118
   Portuguese military expeditions 78
   Ebers Papyrus 15, 43
   ecstasy 363
   Edinburgh 149
   Egypt 49
   heroin epidemic 327, 337
   Egypt, ancient 14–15
   Egyptian opium 145
   EIC (East India Company) 85–6, 87, 88, 96, 99, 108, 112, 163–4, 169, 170–1
   British government’s attempt at regulating 174
   in Canton 109–11
   end of trading days 181
   growth of dominance 163
   opium trade 173–6
   opium trade in India 171, 173
   tea trade 164, 165, 166–7
   Eichengrün, Arthur 240–1
   Eisle, Otto 285
   Eliopoulos, Elias 262–3
   Elliot, Captain Charles 187, 188, 190
   Elphinstone, William 304
   Emily incident (1821) 177–8
   encephalin 343
   endorphins 343
   England see Britain
   Estonia 332
   evidence-based medicine 53
   Ezra, Edward Isaac 264
   Falloppio, Garile 68
   Farmacia Santa Maria Novella 67
   Federal Bureau of Narcotics 262
   Federal Narcotics Control Board 259
   fentanyl 323, 373, 374
   fentanyl lollipops 324–5
   Fertile Crescent 4–5, 25
   field medic (Second World War) 282–3, 287
   Fielding, Henry 140, 142
   Finland 332
   First Opium War 188–90, 193–4, 200
   First World War 276–82
   American casualties 292
   innovations in treatment of wounds and anaesthetics 280
   shortage of medical supplies and morphine 277–9, 280–1
   use of mustard gas by Germans 278
   Fitch, Ralph 84–5
   Fitzgerald, Luke 364, 365
   Fleet Prison (London) 63
   Fleming, Alexander 283
   Flint, James 110–11
   Florus 30
   Fordham, Elias P. 204
   Foreign Narcotics Kingpin Designation Act (1999) 360–1
   F
ortune, Robert 191
   Foundling Hospital (London) 140
   14K Gang 359
   France 46
   Communists in 268
   and Corsican Mafia 267–9
   heroin production 331
   Franks 47
   Friedman, Elizebeth Smith 264
   Galen of Pergamon 23–5, 42, 53, 123
   gambling 142
   Gandamak, Treaty of (1879) 305
   gardens, opium growing in early 20, 61–2
   Garth, Dr Samuel 130–1
   Gawande, Atul 375–6
   Gay-Lussa, Joseph Louis 161
   Geber 40
   Genghis Khan 55
   Germany 70
   attitude towards opium and cocaine 284
   golden age of pharmaceutical production 283–4
   Neolithic settlements 7–8
   Gin Act (1751) 142
   Gin Craze 135–40, 141–2, 145, 363
   Ginsberg, Allen 333, 334
   Glacium flavum see horned poppy
   Gladstone, William 188
   glaucine 5
   Godber, Peter Fitzroy 354, 355
   Godfrey’s Cordial 148, 205
   Gold Cure 230, 256
   Golden Triangle 295–6, 297, 298, 356
   Gondeshapur 35–6
   Goulāo, Joāo 367
   Government of India Act (1833) 181
   Great Bengal Famine (1770) 175
   Greece, ancient 11–13, 16–20
   Green Gangs 263–7, 351
   Grimm, Henry
   The Chinese Must Go 223–4
   Grotius, Hugo
   The Freedom of the Seas 87
   Guam 145–6
   Guangdong 97, 98, 105, 246
   Guangzhou 79
   Guérini, Antoine and Bartélemy 267, 268, 269
   Guild of Physicians and Apothecaries 67
   guilds 66–67
   Canton/Chinese 107–8
   Italian city-state 55
   Gulf War 324
   Gutenberg, Johannes 67
   Habitual Drunkards Act see Drunkards Act
   Habsburg Empire 122
   haemorrhoids 53
   Hague Convention 262, 331
   Hamilton, Lillias 306
   Han dynasty 28–9
   Hansa (Internet) 370
   Hanseatic League 70
   Hanway, Jonas 164
   Essay on Tea 164
   haoma 35, 59
   Harrison Narcotics Tax Act (1914) 255, 256, 259, 275, 276, 277, 339
   Harvey, William 124
   Hastings, Governor General Warren 167, 175
   Hauschild, Dr Fritz 284
   Heath, Edward 286–7
   Heaven and Earth Society see Triads
   Hekmatyar, Gulbuddin 316
   Helmand River Valley Project (Afghanistan) 309–13
   hemlock 19, 53, 62, 64
   henbane (Hyoscyamus niger) 8, 21, 42, 46, 64
   Hendrix, Jimi 341
   Henry the Navigator 72
   Heraclius, Emperor 36
   herbalism, medieval 62
   Herodotus 27
   heroin
   adulteration of 368–9
   Afghanistan production 301, 317, 320, 327
   and Corsican Mafia 269
   creation of Golden Triangle and production of 295–6
   creation of 240–2
   domination of global trafficking of by Triads 360
   early appearances of overdoses 244