The Cancer Chronicles
Page 35
paleo diet
paleo-oncology
Paleo-Oncology (Retsas)
pancreas, 6.1, 10.1
pancreatic cancer, 2.1, 5.1, 7.1, 7.2, 7.3, 10.1, 12.1
papillary fronds
Parkinson’s disease
Pascal, Blaise, 2.1, 2.2, 2.3
“passenger” mutations
Patagonia
Paul of Aegina
Peking man
penicillin, 10.1, 10.2
Pennsylvanian period
Perjeta (pertuzumab)
pertuzumab (Perjeta)
pesticides, 2.1, 7.1, 10.1
naturally occurring, 1.1, 2.1, 7.1
Peto, Richard, 1.1, 7.1, 7.2, 7.3, 10.1, 10.2
Peto’s paradox
PET (positron emission tomography) scan, 2.1, 11.1, 13.1, epl.1
pharmaceutical companies
drugs named by
promotion by
research by, 9.1, 12.1
phenols
phosphoresence
phytochemicals, dubious benefits of
picocuries
pink ribbon campaign, 12.1, 12.2
pitchblende, 5.1, 11.1
placenta, 6.1
plants
metastasis compared to propagation of
tumors in
plasma, 1.1, 3.1
platinum
Pleistocene era, 1.1, 3.1
Pliny
Pokémon (game)
polarization
polio
politics, cancer and, 2.1, 7.1
Politics of Cancer, The (Epstein)
Pollock, Jackson
pollution, as cancer source, 1.1, 7.1, 7.2
polonium
polyps, 2.1, 8.1
pooled analysis
population genetics
Population Reference Bureau
Pott, Percivall
poverty, cancer and, 1.1, 7.1, 7.2, 12.1
praeter naturam (preternatural)
pregnancy
and cancer risk
physiology of, 6.1, 6.2, 10.1
Price, Reynolds
primary cancers, 3.1, 3.2, 3.3
Proctor, Robert
progesterone
progression-free survival
prospective epidemiological studies, 2.1, 10.1
prostate cancer, 1.1, 3.1, 3.2, 7.1, 7.2, 7.3, 10.1, 10.2
as common, 2.1, 3.1, 12.1
decline in, 7.1, 7.2
screening debate in
prostate-specific antigen (PSA), 3.1, 12.1
proteases, 5.1, 10.1
proteome, 9.1, 13.1, epl.1
protons
proto-oncogenes, 5.1, 5.2
pseudopathology
PTEN gene
punctuated equilibrium
Quammen, David
quantum mechanics
quantum physics
rabbits, carcinoma research on, 5.1, 10.1, epl.1
radiation
cancer risk from, 3.1, 3.2, 5.1, 7.1, 7.2, 11.1, 13.1
from microwaves
mutations and
from nuclear blasts
possible benefits of
radiation therapy, 4.1, 5.1, 5.2, 8.1, 8.2, 12.1, 13.1
alternatives to
Joe’s
Nancy’s, 11.1, 13.1
negative effects of, 11.1, 11.2, 12.1
process of
radioactive iodine
radioactivity, 11.1, epl.1
in dinosaur extinction
in mutation
radio frequency
radioisotopes, 2.1, 3.1, 4.1, 7.1, 11.1
radium, 2.1, 5.1, 11.1, 11.2, epl.1
Radium Girls, 5.1, epl.1
radon
cancer risk from, 2.1, 11.1
testing for
Ramazzini, Bernardino, 10.1, 10.2
ras gene, 5.1, 5.2, 5.3
rats, laboratory use of
Rb gene
receptor-interacting protein (RIP)
rectal cancer
Red Dye No. 2
red meat, inconclusive cancer risk from, 2.1, 3.1, 7.1, 10.1, 10.2
reelin gene, 12.1
regeneration, 1.1, 6.1
Relay for Life, 11.1, 13.1
Report on Carcinogens,
“Report to the Nation on the Status of Cancer,”
retinoblastoma
retrospective epidemiological studies, 2.1, 10.1, 13.1
retrovirus
reverse smoking
rhabdomyosarcoma
Riboli, Elio, 10.1, 10.2, 10.3, 10.4, 11.1
Richard J—
Riggs, Elmer
Rigoni-Stern, Domenico
RNA
in genetics
in viruses
Rockefeller Institute for Medical Research
Rockies, formation of
Rome, ancient, 3.1, 5.1
Röntgen, Wilhelm
Rosenberg, Robert
Rothko, Mark
Rothko Chapel
Rothschild, Bruce, dinosaur fossils observed by, 1.1, 1.2
Rothschild, Christine
Rous, Peyton
Royal College of Surgeons
Royal Society of Medicine, 3.1, epl.1
Run for Life
Russia
Ryan, Brandon
saccharine
Sacculina carcini,
St. Jude’s Children’s Research Hospital
St. Mary’s Hospital, London
Salk, Jonas
salmonella, research on
salsify
salt, 10.1, 11.1
Sandia Mountain
San Diego Zoo
Santa Fe, N. Mex., 2.1, 8.1, 11.1, 13.1
sarcomas, 1.1, 1.2, 3.1, 4.1, 5.1, 8.1
Saxon fossil, 3.1, 3.2
Science,
Science of Cancerous Disease from Earliest Times to the Present, The (Wolff)
scrotums, scrotal cancer, 5.1, 10.1
Scythians
seed and soil theory
Self-Consciousness (Updike)
sentinel nodes
sex hormones, 2.1, 2.2, 7.1, 10.1, 10.2
sexual behavior, cancer risk from, 7.1, 7.2, 11.1
sharks, cancer in
shh signaling pathway
Silent Spring (Carson)
sirtuins
size, cancer risk and
skin cancers, 6.1, 7.1, 12.1
smoking
proven cancer risk from, 2.1, 2.2, 2.3, 2.4, 2.5, 3.1, 5.1, 7.1, 7.2, 7.3, 7.4, 7.5, 10.1, 10.2, 10.3, 10.4, 10.5
in radiation studies, 11.1, 11.2
reverse
smoothened (protein)
Society for Developmental Biology, conference of, 6.1, 9.1
Solzhenitsyn, Aleksandr, 12.1, epl.1
sonic hedgehog gene, 6.1, 12.1
soot warts, 5.1, 10.1
South America
spine
dinosaur
metastasis to, 1.1, 1.2
spinthariscope
splenules
squamous cell carcinoma
of head and neck
src gene, 5.1, 5.2
Stand Up to Cancer, 12.1, 12.2
staphylococcus,
Stathopoulos, George
statistics
in cancer research, 12.1, 13.1
in cancer risk, 11.1, 11.2
in survival rate
varying and conflicting interpretations of, 2.1, 3.1, 7.1, 7.2, 7.3, 7.4
Steel Forest
Stegosaurus, 1.1, 1.2
stem cells, 6.1, 9.1, 9.2
stemness
stomach cancer, 3.1, 6.1, 7.1, 7.2, 7.3, 9.1, 10.1, 11.1, 13.1, 13.2
stress
cancer risk from, 7.1, 10.1, 11.1, 13.1
oxidative
stroke
strontium-90
Strouhal, Eugen
sugar
cancer risk from
consumption
Sumpter, Ann
sunlight
/> in circadian disruption
proven cancer risk from, 2.1, 2.2, 3.1, 7.1, 7.2, 13.1
“super Herceptin” (trastuzumab emtansine; T-DM1)
surgeons, 6.1, 8.1, 11.1
surgery, 12.1, 12.2
gastric bypass
Joe’s, epl.1, epl.2
laser
Nancy’s, 4.1, 6.1, 8.1, 11.1
reconstructive
Surveillance, Epidemiology and End Results Program (SEER), 7.1, 7.2, 7.3, 7.4, 7.5
survivors, use of term
Susan (author’s friend)
taphonomic changes
targeted therapies, 8.1, 9.1, 11.1, 12.1, 13.1
Tasmanian devils
Taubes, Gary
Taxol (paclitaxel), 8.1, 8.2, 8.3, 9.1
Taxus brevifolia (Pacific yew tree)
Technology Assessment Office, U.S.
teeth, 3.1, 3.2
Telome Health, Inc.
telomerase, 5.1, 9.1
telomeres, 5.1, 9.1, epl.1
“Ten Crazy Ideas About Cancer,”
teratomas
Tesla, Nikola
tesseract
testicular cancer, 8.1, 10.1
theoretical physics
therioma,
Thiersch, Karl
Thinking Machines
Thomas, Lewis
thyroid cancer, 5.1, 7.1, 11.1, 11.2
tissue bank
topotecan
Train, Russell
transcriptome
translational research, 12.1, 12.2
trastuzumab (Herceptin), 8.1, 9.1, 12.1
trastuzumab emtansine (“super Herceptin”; T-DM1)
triclopyr
trout, cancer in
tuberculosis
tumbleweed (Salsola tragus; Russian thistle)
tumors
benign, 1.1, 1.2, 2.1
compared to organs
composition of
development of, 2.1, 4.1, 5.1, 9.1
of dinosaur bone
embryonic development compared to, 6.1
evolving historical insights on
inflammation and
of jaw, 3.1, epl.1
malignant
mobility of
multiple, 4.1, epl.1
in plants
seeding and proliferation of
as unique
virtual
tumor suppressors, 5.1, 9.1, 9.2, 9.3, 9.4, 12.1, epl.1
Tyrannosaurus rex, 1.1, 1.2
United States Adopted Name Council
University Hospital
Updike, John
uranium, 2.1, 5.1, 11.1
Utah, 1.1, 1.2
uterine cancer, 1.1, 3.1, 3.2, 4.1, 6.1, 7.1, 7.2, 7.3, 8.1
uterine papillary serous carcinoma (UPSC), 8.1, 8.2, 8.3, 8.4, 8.5, 12.1
uterus, 2.1, 4.1, 6.1, 6.2, 10.1
Varmus, Harold
vemurafenib (Zelboraf), 12.1, 12.2
Veratrum californicum lily
vertebrae
dinosaur
mammal
vhl gene
Virchow, Rudolf, 4.1, 10.1
viruses, cancer caused by, 5.1, 7.1, 7.2, 9.1, 9.2, 9.3, 10.1, 10.2
vismodegib (Erivedge)
vitamin D
Vivian (author’s neighbor), 2.1, 2.2, 4.1
Vogelstein, Bert, nts.1, nts.2
Waldron, Tony
Wallace, Charles (character)
Warburg effect
War on Cancer, 7.1, 13.1
watches, glow-in-the-dark dials for
Watras, Stanley
Watson, James, 5.1, 9.1, 10.1
weeds, as metaphor for cancer, 4.1, 13.1
Weinberg, Robert, 9.1, 9.2, 13.1
Westinghouse, George
whales, low incidence of cancer in
Whitehead Institute
Whole Life, A (Price)
“Why Don’t All Whales Have Cancer?,”
Willett, Walter C.
Wind in the Door, A (L’Engle)
Witzke, Brian
Wolff, Jacob
women
cancer risks for
in radon studies
Wonder, Stevie
World Cancer Research Fund
World Health Organization, 7.1, 13.1
Wrinkle in Time, A (L’Engle)
Xing
x-rays, 1.1, 2.1, 2.2, 3.1, 3.2, 3.3, 13.1
in cancer therapy, 5.1, 11.1
as cause of cancer, 5.1, 5.2, 7.1, 11.1
possible benefits of
Yamagiwa, Katsusaburo, 10.1, epl.1
Yamaguchi, Tsutomo
Yampa Plateau
Zahrawi, Abu al-Qasim al-
Zbtb7 (oncogene)
Zelboraf (vemurafenib), 12.1, 12.2
zinc finger
zinc sulfide, 5.1, epl.1
A NOTE ABOUT THE AUTHOR
George Johnson has written about science for The New York Times, National Geographic Magazine, Slate, Scientific American, Wired, The Atlantic, and other publications. His nine books, which are being translated into fifteen languages, include The Ten Most Beautiful Experiments and Fire in the Mind: Science, Faith, and the Search for Order. He has twice been a finalist for the Royal Society’s science book prize. A winner of the AAAS Science Journalism Award, he is codirector of the Santa Fe Science Writing Workshop and a former Alicia Patterson fellow. He lives in Santa Fe, New Mexico, and can be found on the Web at talaya.net.
ALSO BY GEORGE JOHNSON
The Ten Most Beautiful Experiments
Miss Leavitt’s Stars: The Untold Story of the Woman Who Discovered How to Measure the Universe
A Shortcut Through Time: The Path to the Quantum Computer
Strange Beauty: Murray Gell-Mann and the Revolution in Twentieth-Century Physics
Fire in the Mind: Science, Faith, and the Search for Order
In the Palaces of Memory: How We Build the Worlds Inside Our Heads
Machinery of the Mind: Inside the New Science of Artificial Intelligence
Architects of Fear: Conspiracy Theories and Paranoia in American Politics