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Connectome

Page 42

by Sebastian Seung

]

  molecular interventions for, [>]

  See also Reconnection; Regeneration; Reweighting of synapse; Rewiring of brain

  Fox, Michael J., [>]

  Fracastoro, Girolamo, [>]–[>]

  France, Anatole, [>]–[>], [>], [>], [>]

  Franklin, Rosalind, [>], [>]

  Freezing of body constituents, [>]–[>]

  Freezing of corpses, [>]

  Freischütz, Der (von Weber opera), [>]

  Fried, Itzhak, [>]–[>], [>], [>], [>], [>]

  Frith, Uta, [>]

  Frontal lobe, [>]–[>], [>], [>]

  and autism, [>]

  and linguistic functions, [>]

  and schizophrenics, [>]

  Frontal lobotomy, [>], [>]–[>]

  Frost, Robert, [>]

  Fukushima, Kunihiko, [>]

  Futuristic fantasies, [>]

  Galaxy Zoo project, [>]

  Galileo Galilei, [>], [>], [>]

  Gall, Franz Joseph, [>], [>], [>]

  Galton, Francis, [>]–[>], [>], [>], [>]

  Gambling, [>]

  and Pascal’s Wager, [>]–[>]

  Gamma-aminobutyric acid (GABA), [>], [>]

  Gauguin, Paul, [>]

  Gauss, Carl, [>]

  Geigy, J. R., pharmaceutical company, [>]

  General intelligence as simplistic, [>]

  Genes, [>]

  and autism or schizophrenia, [>]

  Bernal on future manipulation of, [>]

  and connectome, [>], [>], [>]

  expressing of, [>]

  and growth of axon, [>]–[>]

  Mendel’s discovery of, [>]

  and neuronal connectome, [>]

  neurons influenced by, [>]

  in study of C. elegans, [>]–[>]

  and synapse creation, [>]

  in wiring of brain, [>], [>]

  Gene therapy, [>]

  for Parkinson’s disease, [>]

  Genetic code, [>]

  Genetic engineering, and mental disorders in animals, [>]

  Genetic testing

  on fetus, [>]

  for Huntington’s disease (HD), [>]–[>]

  Genie (abused child), [>], [>], [>]

  Genome, [>], [>], [>]

  multiple meanings of, [>]

  Genome, human

  excerpt from, [>]

  as explanation of differences, [>]

  of fraternal twins, [>]

  as unchangeable, [>], [>], [>]

  viewing of, [>]

  Genomics, [>]–[>], [>], [>]–[>]

  and autism or schizophrenia, [>]–[>]

  and connectomes, [>]

  progress of, [>], [>]

  Giza, pyramid of, [>]–[>]

  Glial cells, [>]

  Glutamate, [>], [>]

  God

  humanity making itself into (transhumanism), [>]

  and Pascal’s Wager, [>]–[>]

  Gödel, Kurt, [>]

  Goldschmidt, Richard, [>]

  Golgi, Camillo, [>], [>], [>], [>]

  Golgi staining method, [>]–[>], [>], [>], [>], [>], [>], [>]

  Gould, Elizabeth, [>], [>], [>]

  Graham, Sonny, [>]–[>]

  “Grand challenges,” [>]

  “Grandmother cell” theory of perception, [>]

  Gray matter, [>], [>], [>]. See also Cortex

  Greeks (ancient), and Fates, [>]

  Greenough, William, [>], [>], [>], [>]

  Grey, Aubrey de, [>]

  Grossberg, Stephen, [>]

  “Growth cone,” [>]

  Guerre, Martin, [>], [>]

  Gujrat, Pakistan, shrine in, [>]–[>]

  Hall, David, [>], [>], [>]–[>]

  Harris, Kristen, [>], [>], [>], [>]

  Harvard University, ultramicrotome in, [>]–[>], [>]

  Harvey, Thomas, [>]

  Hawking, Stephen, [>]–[>]

  Hayek, Friedrich, [>]

  Hayworth, Ken, [>]–[>], [>]–[>]

  Heaven, [>]

  as computer simulation, [>]–[>]

  Hebb, Donald, [>]

  Hebbian synaptic plasticity, [>], [>], [>], [>], [>], [>]

  disabling of, [>]

  as learning, [>]

  and potential to learn, [>]

  variant of, [>]

  Hebbian strengthening, [>]

  Heidelberg, [>]

  Helmstaedter, Moritz, [>]

  Hemispherectomy, [>]

  Hierarchical organization of neurons, in perception, [>]

  and memory “grounding,” [>]–[>]

  Hierarchical perceptron model for brain, [>]

  Hippocampus, [>], [>], [>]

  fluoxetine effect on, [>]

  posterior, [>]

  and schizophrenia, [>]

  study as enlarging, [>]

  “Hive mind,” [>]

  Homunculus, motor or sensory, [>]–[>], [>], [>]

  Hubel, David, [>], [>]

  Human Connectome Project, [>], [>]

  Human Genome Project, [>], [>], [>]

  Human immunodeficiency virus (HIV), [>]

  Hume, David, [>]

  Huntington’s disease (HD), [>]–[>], [>]

  Huxley, Aldous, [>]

  HVC (region of bird brain), [>]–[>], [>], [>], [>]–[>], [>]

  Hypothermia, and memory, [>]–[>]

  Hypotheses, role of in science, [>]

  and tools of measurement, [>]

  I Am Your Child Foundation, [>]

  IBM, and Markram, [>]

  Ideas, abstract, [>]

  Image analysis, automating of, [>]

  Imipramine, [>]–[>]

  Immortality, [>]–[>]

  as information preservation, [>]–[>]

  Implicit (nondeclarative) memory, [>]–[>]

  of birds, [>]–[>]

  acquisition of, [>]–[>]

  as synaptic chain, [>]–[>], [>]

  Inbreeding, [>]

  Individual differences

  and averages, [>]

  and brain, [>], [>], [>], [>]

  connectionism as explaining, [>]

  connectomes as basis for, [>]–[>], [>]

  and smaller connectomes, [>]

  between twins, [>]

  Inductive (“data-driven”) approach to science, [>]

  Inferior colliculus, [>]

  Inferior parietal lobule, [>]

  Infinite regress, and neuronal explanation of perception, [>]

  Information, self as, [>]–[>]

  Information theoretic death, [>]

  Inherited traits, DNA as source of, [>]. See also Nature-nurture relation

  Inhibition, need for, [>]

  Inhibitory neurons, [>]–[>], [>]

  and divergent synaptic chains, [>]

  and sedatives, [>]

  Inhibitory synapses, [>], [>]

  Insanity. See Mental disorders and disabilities; Schizophrenia

  Intelligence, [>]

  and brain size

  correlation between, [>]

  in Anatole France and Ivan Turgenev, [>]–[>]

  and Galton’s approach, [>]–[>], [>]

  multiple, [>]

  Pearson’s categorization of, [>]

  Intelligence Amplification (IA), [>]

  Intermarriage between cousins, and microcephaly, [>]

  Interneurons, [>]

  Intracellular recording, [>]–[>]

  Inverted-image telescope experiment, [>]

  Ion channel, [>], [>], [>], [>], [>]

  iPhone, as modern miracle, [>]

  Iproniazid, [>]–[>]

  IQ

  as simplistic, [>]

  frontal and parietal lobes correlated with, [>]–[>]

  Irreversibility, [>]–[>]

  Jain, Viren, [>]–[>]

  James, William, [>]

  Jesuit maxim on childhood indoctrination, [>]

  John the Baptist, [>]

  Kandel, Eric, [>]–[>], [>]

  Kanizsa triangle, [>], [>]–[>]

  Kanner, Leo, [>]–[>], [>]
/>
  Karten, Harvey, [>]

  Kasparov, Garry, [>]

  Kasthuri, Narayanan “Bobby,” [>]

  Keith, Sir Arthur, [>]

  Kelvin, Lord, [>]

  Kennard Principle, [>]

  Khufu (pharaoh), [>]–[>]

  Knives, [>]

  Knott, Graham, [>]

  Knudsen, Eric, [>]–[>], [>]

  Koch, Christof, [>]

  Koch, Robert, [>]

  Koskinas, Georg, [>]

  Kurzweil, Ray, [>], [>]

  Labyrinth, [>], [>]

  Lander, Eric, [>]

  Language

  Broca-Wernicke model of, [>], [>], [>]

  replacement for, [>]

  and hemispherectomy, [>]

  learning of in childhood, [>]

  by Genie, [>]

  in left hemisphere, [>]

  and stroke, [>]

  and synaptic chain, [>]

  Languages, lost, [>]–[>]

  Large Hadron Collider (LHC), [>]

  Lashley, Karl, [>]–[>], [>], [>]

  Las Vegas, [>]

  Lateral geniculate nucleus (LGN), [>], [>]

  Lateralization, cerebral, [>], [>]

  Law of Dynamic Polarization, [>]

  Laws of Behavior Genetics, [>], [>]

  Learning

  and connectomes, [>]

  connectome change as cause, [>]

  critical period for, [>]–[>], [>]

  and vision experiments, [>]–[>], [>], [>]

  as expansion of cortical areas, [>]

  and four R’s of connectome change, [>] (see also Reconnection; Regeneration; Reweighting of synapse; Rewiring of brain)

  by machine, [>], [>]

  and neocortical plasticity, [>]

  and redundant representation, [>]–[>]

  and sparse connectivity, [>]–[>]

  synapse creation/elimination in, [>]

  Leeuwenhoek, Antonie van, [>]–[>], [>]

  Leibniz, Gottfried Wilhelm

  and calculus, [>]

  optimism of, [>]–[>]

  and Kurzweil, [>]

  on perception, [>], [>], [>]

  on power of reasoning, [>]

  and soul, [>]

  Leighton, Stephen, [>]

  Lenin, Vladimir, embalmed, [>]

  Levi-Montalcini, Rita, [>]

  LGN (lateral geniculate nucleus), [>], [>]

  Lichtman, Jeff, [>], [>]

  Life extension, [>]–[>]. See also Cryonics; Plastination

  Light microscopy, [>], [>]

  serial, [>]

  Limitless Future, The (promotional video), [>]

  Linear A script, [>]

  Linear B script, [>], [>]–[>]

  Lissencephaly, [>]–[>], [>]

  Live Long Enough to Live Forever (Kurzweil), [>]–[>]

  Lobotomy, [>]

  Localizationism (cortical or cerebral), [>], [>]

  Broca’s discoveries in, [>]–[>]

  criticism of, [>]

  and genius, [>]–[>]

  and Lashley, [>], [>]

  and symptoms of brain injury, [>]–[>]

  Wernicke’s discoveries in, [>]–[>]

  Loci, method of, [>]

  Locke, John, [>], [>], [>]–[>]

  Lock-and-key metaphor for neurotransmission, [>], [>], [>]

  Loewi, Otto, [>]

  Longitudinal fissure, [>], [>]

  Lorente de Nó, Rafael, [>]

  Lost languages, [>]–[>]

  Machine learning, [>], [>]

  Machines

  bodies viewed as, [>], [>]

  and Leibniz on perception, [>]

  and reanimation, [>]

  Magic bullet, [>], [>]

  Magnetic resonance imaging (MRI), [>]–[>], [>], [>], [>], [>], [>], [>]–[>], [>]–[>]

  Magnetic resonance imaging, diffusion (dMRI), [>], [>]–[>], [>]

  Magnetic resonance imaging, functional (fMRI), [>]–[>], [>], [>], [>]–[>], [>]

  Map(s), [>]–[>], [>]

  Mapping of brain

  electrical stimulation for, [>], [>]–[>]

  of white-matter axons, [>], [>]–[>]

  See also Brodmann’s map

  Markram, Henry, [>]–[>], [>], [>]

  Massachusetts Institute of Technology, Artificial Intelligence Laboratory of, [>]

  Materialism, doctrine of, [>]

  uploader’s rebuke to, [>]–[>]

  Maupassant, Guy de, [>]

  Max Planck Institute for Medical Research, [>]

  Max Planck Society, [>]

  Mazur, Peter, [>]

  “Meaning of life,” and transhumanism, [>]

  Mechanism, doctrine of, [>]–[>], [>]

  uploader’s rebuke to, [>]–[>]

  Medial geniculate nucleus (MGN), [>]

  Medial temporal lobe (MTL), [>]–[>]

  and memory, [>]–[>]

  Medications. See Drugs

  Memory(ies), [>]–[>], [>]

  and association, [>], [>], [>]–[>], [>]–[>], [>]

  of birds, [>]

  and case of H.M., [>]

  and CA3 region, [>], [>], [>]

  connectionist theory of, [>]

  and connectomes, [>]

  memories read from, [>], [>], [>]–[>], [>], [>]

  memories read from (birds), [>]–[>]

  memories read from (dead humans), [>], [>]

  MTL prominent in, [>]–[>]

  “crystallized,” [>]

  difficulty in testing hypotheses on, [>]–[>]

  dual-trace theory of, [>]–[>]

  and stability-plasticity dilemma, [>]–[>]

  “grounding” of, [>]–[>]

  and hippocampus, [>]

  and information overload, [>]

  and material structure, [>]–[>]

  and persistence of synaptic changes, [>]

  and persistent spiking, [>]–[>]

  and reconnection, [>]–[>]

  and reweighting, [>]–[>], [>]–[>]

  and sparse connectivity, [>]

  types of

  declarative (explicit), [>]–[>], [>]

  nondeclarative (implicit), [>]–[>]

  and “white paper” metaphor, [>]

  Mendel, Gregor, [>]–[>]

  Mental disorders and disabilities, [>], [>]

  Alzheimer’s, [>], [>], [>], [>], [>]

  autism, [>]–[>], [>]–[>], [>], [>]–[>] (see also Autism)

  and behavior change, [>]–[>]

  bipolar disorder, [>]

  and brain connectivity (MRI as finding correlations), [>]

 

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